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首页> 外文期刊>Clinical and experimental pharmacology & physiology >Degree of adaptability of the somatosensory cortex to change: Prospects for integration of bone-mounted dental prostheses.
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Degree of adaptability of the somatosensory cortex to change: Prospects for integration of bone-mounted dental prostheses.

机译：体感皮层变化的适应程度：骨装式牙科修复体的整合前景。

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SUMMARY 1. The topographic representation of the body surface in the somatosensory cortex provides an important model system for the in vivo study of neuronal plasticity, induced changes in somatotopy providing a direct measure of plasticity not available in most parts of the central nervous system. 2. Over the past two decades, animal experimentation in a number of laboratories has shown a remarkable degree of adaptability of the cortical representation following peripheral lesions and has had a widespread influence by challenging the once-accepted dogma that the brain is a structurally fixed organ. 3. Although some aspects of original stimulation will be missing, it is likely that receptors stimulated through bone conduction and compression by bone-mounted dental prostheses preserve some of the geometric and temporal relationships of original stimulation. By analogy with data obtained from the forearm representations, it would be expected that many features of the original cortical representations will be recreated. 4. There are also examples in the literature of perceptual learning without gross changes to the cortical representation (some being within a class of adaptability known as gain control) and it is likely that perceptual integration of many dental prostheses occurs within the limits of these neural adaptation mechanisms.
机译：概述1.体感皮层中体表的地形图表示为体内研究神经元可塑性提供了重要的模型系统，诱导的体细胞变化提供了直接测量中枢神经系统大多数地方所没有的可塑性。 2.在过去的二十年中，在许多实验室进行的动物实验表明，皮层代表在周围病变后具有显着的适应性，并且通过挑战曾经被接受的教条认为大脑是结构固定的器官而产生了广泛的影响。 。 3.尽管原始刺激的某些方面将丢失，但通过骨传导式假牙通过骨传导和压缩刺激的受体可能保留了原始刺激的某些几何和时间关系。通过与从前臂表征中获得的数据进行类比，可以预期将重建原始皮层表征的许多特征。 4.文献中也有一些例子，知觉学习的皮质表现没有明显变化（有些处于一类称为增益控制的适应性范围内），许多假牙的知觉整合很可能发生在这些神经的极限范围内。适应机制。

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