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首页> 外文期刊>Clinical and investigative medicine: Medecine clinique et experimentale >Association between the burden of disease and research funding by the Medical Research Council of Canada and the National Institutes of Health. A cross-sectional study.
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Association between the burden of disease and research funding by the Medical Research Council of Canada and the National Institutes of Health. A cross-sectional study.

机译：疾病负担与加拿大医学研究理事会和美国国立卫生研究院的研究经费之间的关联。横断面研究。

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BACKGROUND: The Medical Research Council of Canada (MRCC) is the major Canadian agency responsible for funding biomedical health research in this country. Disease-specific funding by the United States National Institutes of Health (NIH) has been studied and is not independent of burden-of-disease parameters. We tested the association between disease-specific MRCC funding, disease-specific NIH funding and various burden-of-disease parameters. METHOD: Information on 1994/99 MRCC funding was obtained from the MRCC database for 29 diseases. NIH funding and burden-of-disease counterparts for the year 1996 were gleaned from a recent publication. The association between data series was measured by correlation coefficients. RESULTS: Disease-specific incidence, mortality and years-of-life lost did not correlate significantly with 1994/99 disease-specific MRCC funding but prevalence (r = 0.54, p = 0.005) and disability-adjusted life-years did (r = 0.48, p = 0.009). A correlation coefficient of 0.50 (p = 0.006) was calculated between 1996 NIH funding and 1996/97 MRCC funding. Two disease categories, cirrhosis and alcohol abuse, received a greater percentage of funds from the NIH than from the MRCC. Two other disease categories, epilepsy and perinatal disease, received a greater percentage of funds from the MRCC than from the NIH. CONCLUSIONS: Disease-specific MRCC grants in the past 5 years correlated with 2 of the usual burden-of-disease parameters: disability-adjusted life-years and disease prevalence. A statistically-significant correlation was observed between disease-specific grants awarded by the MRCC and the NIH.
机译：背景：加拿大医学研究理事会（MRCC）是加拿大主要的机构，负责资助加拿大的生物医学健康研究。美国国立卫生研究院（NIH）已研究了针对特定疾病的资金，并且该资金并非独立于疾病负担参数。我们测试了特定疾病的MRCC资金，特定疾病的NIH资金与各种疾病负担参数之间的关联。方法：从MRCC数据库中获得了29种疾病的1994/99 MRCC资助信息。从最近的出版物中收集了NIH在1996年的资金和疾病负担对应物。数据序列之间的关联通过相关系数来衡量。结果：特定疾病的发病率，死亡率和生命年限与1994/99特定疾病的MRCC资助没有显着相关，但患病率（r = 0.54，p = 0.005）和残疾调整生命年确实相关（r = 0.48，p = 0.009）。在1996年NIH资助与1996/97 MRCC资助之间，相关系数为0.50（p = 0.006）。肝硬化和酒精滥用这两个疾病类别从NIH获得的资金比例要比MRCC更大。 MRCC收到的其他两个疾病类别（癫痫病和围产期疾病）所占的资金比例要高于NIH。结论：在过去的5年中，针对特定疾病的MRCC补助金与2种常见疾病负担参数相关：残疾调整生命年和疾病患病率。在MRCC和NIH授予的特定疾病补助金之间观察到了统计学上显着的相关性。

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