Hepcidin: an important new regulator of iron homeostasis.

Hugman A

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Hepcidin: an important new regulator of iron homeostasis.

机译：Hepcidin：铁稳态的重要新调节剂。

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Summary Hepcidin is an important and recently discovered regulator of iron homeostasis. There is strong evidence in support of an important role for hepcidin dysregulation in the pathogenesis of iron overload disorders, and possibly in the aetiology of the anaemia of chronic disease. Further research is needed into the physiology of hepcidin to elucidate the relative contributions of the liver and kidney to its production and metabolism. The study of the differential roles of prohepcidin and its metabolites as well as the significance of their serum and urine levels will enhance our understanding of their role in iron metabolism.

机译：总结铁调素是铁稳态的重要且最近发现的调节剂。有强有力的证据支持铁调素调节异常在铁超负荷疾病的发病机理中可能起重要作用，并可能在慢性疾病性贫血的病因中起重要作用。 Hepcidin的生理学需要进一步研究，以阐明肝脏和肾脏对其产生和代谢的相对作用。对前丙烯素及其代谢物的不同作用及其血清和尿液水平的意义的研究将增进我们对它们在铁代谢中作用的理解。

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《Clinical and laboratory haematology》 |2006年第2期|共9页
作者
Hugman A;
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正文语种 eng
中图分类内科学;
关键词
Iron; Homeostasis; hepcidin; Role; Pathogenesis; 铁; 体内稳态; 角色;

机译：Iron;Homeostasis;hepcidin;Role;Pathogenesis;铁;体内稳态;角色;

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1. Hepcidin: the main regulator of iron homeostasis. [J] . Franchini M Clinical chemistry and laboratory medicine: CCLM . 2011,第2期

机译：Hepcidin：铁稳态的主要调节剂。
2. Transport of hepcidin, an iron-regulatory peptide hormone, into retinal pigment epithelial cells via oligopeptide transporters and its relevance to iron homeostasis. [J] . Chothe PP, Gnana Prakasam JP, Ananth S, Biochemical and Biophysical Research Communications . 2011,第2期

机译：铁调素肽hepcidin通过寡肽转运蛋白转运到视网膜色素上皮细胞中，并与铁稳态相关。
3. Transport of hepcidin, an iron-regulatory peptide hormone, into retinal pigment epithelial cells via oligopeptide transporters and its relevance to iron homeostasis. [J] . Chothe PP, Gnana Prakasam JP, Ananth S, Biochemical and Biophysical Research Communications . 2011,第2期

机译：铁调素肽hepcidin通过寡肽转运蛋白转运到视网膜色素上皮细胞中，并与铁稳态相关。
4. Miraxanthin-V, Liriodenin and Chitranone are Hepcidin Antagonist In silico for Iron Deficiency Anemia [C] . S Yotriana, YH Suselo, Muthmainah International Conference on Advanced Materials for Better Future . 2018

机译：Miraxanthin-V，Liriodenin和Chitranone是Silico的辛辛素拮抗剂，用于缺铁性贫血
5. Novel Regulators of Mitochondrial and Cellular Iron Homeostasis. [D] . Bayeva, Marina. 2012

机译：线粒体和细胞铁稳态的新型调节剂。
6. Errata: Lee DH Zhou LJ Zhou Z et al. Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis. Blood. 2010;115(15):3136–3145. [O] . -1

机译：勘误表：Lee DHZhou LJZhou Z等。 Neogenin抑制HJV分泌并调节BMP诱导的hepcidin表达和铁稳态。血液。 2010; 115（15）：3136-3145。
7. A multi-scale model of hepcidin promoter regulation reveals factors controlling systemic iron homeostasis. [O] . Guillem Casanovas, Anashua Banerji, Flavia d'Alessio, 2014

机译：hepcidin启动子调节的多尺度模型揭示了控制系统铁稳态的因子。
8. Hepcidin: A Critical Regulator Of Iron Metabolism During Hypoxia [R] . Hintze, K. J., McClung, J. P. 2011

机译：Hepcidin：缺氧期间铁代谢的关键调节因子

Hepcidin: an important new regulator of iron homeostasis.

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