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首页> 外文期刊>Clinical and laboratory haematology >Significant differences between capillary and venous complete blood counts in the neonatal period.
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Significant differences between capillary and venous complete blood counts in the neonatal period.

机译：新生儿期间毛细血管和静脉全血细胞计数之间的显着差异。

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The normal capillary and venous hematologic values for neonates have not been defined clearly. It is well known that capillary blood has higher hemoglobin (Hb) and hematocrit (Hct) values than venous blood. In a recent study, we reported differences between capillary and venous complete blood counts (CBC) in healthy term neonates on day 1 of life. The aim of this study was to extend our previous investigation. Term neonates (n=141) were stratified into four groups by days of postnatal age: group 2 (day 7, n=38), group 3 (day 14, n=35), group 4 (day 21, n=32) and, group 5 (day 28, n=36). Data from our previous study were included in the statistical analysis as group 1 (day 1, n=95). A CBC and differential count were carried out on each capillary and venous sample drawn simultaneously. Within each group, the mean and standard deviation for each parameter in capillary and venous blood were calculated and then compared using the paired sample t-test. In all groups, the capillary blood samples had higher Hb, Hct, red blood cell (RBC), white blood cell (WBC), and lymphocyte counts. In each group, venous platelet counts were significantly higher than the corresponding capillary values. There was also a trend toward higher venous mean corpuscular volume, higher capillary polymorphonuclear leukocyte (PML) count and mean platelet volume in all groups. In both capillary and venous blood, Hb, Hct, RBC, MCV values and WBC, lymphocyte, PML counts decreased and platelet counts increased steadily during neonatal period. This study reveals that CBC parameters and differential counts may differ depending on the blood sampling used. The findings underline the importance of considering the sample source when using hematologic reference ranges for healthy or septic neonates. When interpreting results, the term 'peripheral blood' should be replaced with 'capillary blood' or 'venous blood' so that an accurate assessment can be made.
机译：新生儿的正常毛细血管和静脉血液学值尚未明确定义。众所周知，毛细血管血比静脉血具有更高的血红蛋白（Hb）和血细胞比容（Hct）值。在最近的一项研究中，我们报道了健康足月新生儿生命第一天的毛细血管和静脉全血细胞计数（CBC）之间的差异。这项研究的目的是扩展我们以前的研究。足月新生儿（n = 141）按出生后的天数分为四组：第2组（第7天，n = 38），第3组（第14天，n = 35），第4组（第21天，n = 32）。第5组（第28天，n = 36）。我们先前研究的数据作为第1组纳入统计分析（第1天，n = 95）。在同时抽取的每个毛细管和静脉样本上进行CBC和差异计数。在每组中，计算毛细管和静脉血中每个参数的平均值和标准偏差，然后使用配对样本t检验进行比较。在所有组中，毛细血管血样的Hb，Hct，红细胞（RBC），白细胞（WBC）和淋巴细胞计数均较高。在每组中，静脉血小板计数显着高于相应的毛细血管值。在所有组中，还有静脉平均红细胞体积增加，毛细管多形核白细胞（PML）计数增加和平均血小板体积增加的趋势。在新生儿期间，在毛细血管和静脉血中，Hb，Hct，RBC，MCV值以及WBC，淋巴细胞，PML计数均下降而血小板计数稳定地上升。这项研究表明，根据所使用的血液采样，CBC参数和差异计数可能会有所不同。这些发现强调了在健康或脓毒症新生儿使用血液学参考范围时考虑样本来源的重要性。在解释结果时，术语“外周血”应替换为“毛细血管血”或“静脉血”，以便进行准确的评估。

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