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非線形回路と可変閾値を用いた埋込型神経信号検出?伝送回路の開発

机译:利用非线性电路和可变阈值开发可植入神经信号检测/传输电路

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摘要

In the neuroscience and physiology fields, studies on implantable neural signal detection and transmission systems have clarified the relationship between motor and sensory activities and neural activity. This technique is applicable to handicapped persons in areas of brain-computer interface (BCI) and bionic arm. In this study, we developed a multi-channel neural signal recording system that is capable of measuring neural signals steadily even when the signal amplitude decreases and the noise level increases during long-term measurement. In a previous study, we developed and tested a multi-channel system that simultaneously detected spikes, and calculated the firing frequency. The system comprises a neural signal enhancer with non-linear circuitry and a spike detector. We demonstrated that the performance of the system was sufficient to be used as an embedded spike detector. However, there was an issue that power consumption of the circuit was not optimized. In this study, we reduced the power consumption of the system and evaluated its performance for long-term measurements in a rat. The test results with the improved hardware showed that the new system consumes substantially less power than the previous system. The experiments of long-term spike measurement showed that stable spike measurements were possible using a neural signal enhancer with non-linear circuitry.
机译:在神经科学和生理学领域,对植入式神经信号检测和传输系统的研究阐明了运动和感觉活动与神经活动之间的关系。此技术适用于脑机接口(BCI)和仿生手臂领域的残障人士。在这项研究中,我们开发了一种多通道神经信号记录系统,即使在长期测量过程中信号幅度减小且噪声级别增加时,也能够稳定地测量神经信号。在先前的研究中,我们开发并测试了一个多通道系统,该系统可以同时检测尖峰并计算点火频率。该系统包括具有非线性电路的神经信号增强器和尖峰检测器。我们证明了该系统的性能足以用作嵌入式尖峰检测器。但是,存在电路的功耗未被优化的问题。在这项研究中,我们降低了系统的功耗并评估了其在大鼠中长期测量的性能。使用改进的硬件的测试结果表明,新系统比以前的系统消耗的功率少得多。长期峰值测量的实验表明,使用带有非线性电路的神经信号增强器可以进行稳定的峰值测量。

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