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首页> 外文期刊>Clinica chimica acta: International journal of clinical chemistry and applied molecular biology >Urine sediment analysis: Analytical and diagnostic performance of sediMAX - a new automated microscopy image-based urine sediment analyser.
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Urine sediment analysis: Analytical and diagnostic performance of sediMAX - a new automated microscopy image-based urine sediment analyser.

机译：尿沉渣分析：sediMAX的分析和诊断性能-一种新型的基于自动显微镜图像的尿沉渣分析仪。

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BACKGROUND: We evaluated the analytical and diagnostic performance of sediMAX (77 Elektronika, Budapest, Hungary), a new automated microscopy image-based urine sediment analyser (which in some countries is also called Urised) in comparison with visual phase-contrast microscopy. METHODS: Precision, linearity, carry-over and method comparison were carried out according to well-established guidelines. The diagnostic performance with respect to visual phase-contrast microscopy was evaluated with results from two centres (n(1)=910, n(2)=1233). Uncentrifuged urine samples were used in visual microscopy in centre 1, while urine sediments were used in centre 2. RESULTS: Within-run precision for RBC was 17.8% and 6.7% at 18xE6 RBC/L and 447xE6 RBC/L respectively and for WBC it was 17% and 4.4% at 4xE6 WBC/L and 258xE6/L respectively. Between-run imprecision for RBC was 14.7% for 30xE6/L and 7.2% for 283xE6/L. For WBC it was 5.4% at 25xE6/L and 3% at 166xE6/L. In both studies areas under ROC curves (AUC) were 80-90% for RBC, WBC, squamous epithelial cells, yeast and calcium-oxalate crystals. For non-squamous epithelial cells and pathological and hyaline casts the AUC ranged 73-74%. There was no carry-over. CONCLUSIONS: The sediMAX is well able to count and identify RBC, WBC, squamous epithelial cells, yeast, bacteria and calcium-oxalate crystals. Recognition of pathological casts and non-squamous epithelial cells is adequate but needs to be improved.
机译：背景：与视觉相差显微镜相比，我们评估了sediMAX（77 Elektronika，布达佩斯，匈牙利）的分析和诊断性能，这是一种新型的基于自动显微镜图像的尿沉渣分析仪（在某些国家也被称为Urised）。方法：按照公认的准则进行精密度，线性，残留和方法比较。通过两个中心的结果（n（1）= 910，n（2）= 1233）评估了关于视觉相差显微镜的诊断性能。未离心的尿液样本用于中心1的视觉显微镜检查，而尿液沉积物用于中心2的结果。在4xE6 WBC / L和258xE6 / L下分别为17％和4.4％。 RBC的运行间不准确度对于30xE6 / L为14.7％，对于283xE6 / L为7.2％。对于WBC，在25xE6 / L下为5.4％，在166xE6 / L下为3％。在这两个研究中，RBC，WBC，鳞状上皮细胞，酵母和草酸钙晶体的ROC曲线（AUC）下的面积均为80-90％。对于非鳞状上皮细胞以及病理和透明管型，AUC为73-74％。没有结转。结论：sediMAX能够很好地计数和鉴定RBC，WBC，鳞状上皮细胞，酵母，细菌和草酸钙晶体。病理模型和非鳞状上皮细胞的识别是足够的，但需要改进。

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