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首页> 外文期刊>Comprehensive psychiatry. >Subjective quality of life in patients with chronic schizophrenia: relationships between psychosocial and clinical characteristics.
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Subjective quality of life in patients with chronic schizophrenia: relationships between psychosocial and clinical characteristics.

机译：慢性精神分裂症患者的主观生活质量：社会心理与临床特征之间的关系。

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BACKGROUND: Using the theoretical framework of quality of life (QOL), many studies have demonstrated that the beliefs individuals hold about their QOL are important in predicting health outcomes. This study tested the Taiwanese version of the World Health Organization Quality of Life-Brief (WHOQOL-BREF) assessment in schizophrenia patients. The WHOQOL-BREF is a cross-cultural and widely used measure for assessing health-related QOL. This brief version of the questionnaire derived from the concepts included in the 100-item WHOQOL questionnaire was adapted for use in Taiwan. METHODS: In the current cross-sectional study, 104 patients who met Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for schizophrenia or schizoaffective disorder according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria were recruited and independently interviewed using the Taiwanese version of the WHOQOL-BREF. Patients were also examined using various other scales assessing insight, symptom severity, general psychopathology, and antipsychotic-induced side effects. In addition, we analyzed demographic data, clinical variables, and several self-rating scales as correlates of the Taiwanese version of the WHOQOL-BREF. RESULTS: As predicted, age, onset of illness, insight measures, symptom severity, general psychopathology, and antipsychotic-induced side effects were all significantly related to the QOL scores. Multiple regression analyses revealed that depressive symptoms, antipsychotic-induced parkinsonism side effects, hopelessness, and age at illness onset were the 4 strongest predictors of subjective QOL in schizophrenia patients. These variables accounted for 39.2% of the total variance of this QOL model. CONCLUSIONS: The results suggest that the WHOQOL-BREF is a promising model for mental assessing health problems in schizophrenia patients. Furthermore, the present findings highlight the importance of understanding the complex nature of the concept of QOL. Our study also supports the belief that different domains of QOL are likely to have different predictors.
机译：背景：使用生活质量（QOL）的理论框架，许多研究表明，个人对自己的QOL的信念在预测健康结果方面很重要。这项研究测试了世界卫生组织对精神分裂症患者的生活质量简述（WHOQOL-BREF）评估的台湾版本。 WHOQOL-BREF是一种跨文化且广泛用于评估与健康相关的QOL的措施。这份简短的问卷调查表是从100项WHOQOL问卷调查表中包含的概念衍生而来的，适用于台湾。方法：在本项横断面研究中，招募了104名符合《精神障碍诊断和统计手册》，《精神分裂症或精神分裂性情感障碍第四版标准》，《精神障碍诊断和统计手册》，第四版标准的患者，并使用台湾版的WHOQOL-BREF。还使用各种其他量表对患者进行了检查，以评估见识，症状严重程度，一般精神病理学和抗精神病药物引起的副作用。此外，我们分析了人口统计学数据，临床变量和几种自评量表，作为台湾版WHOQOL-BREF的相关数据。结果：正如预期的那样，年龄，疾病发作，洞察力措施，症状严重程度，一般精神病理学和抗精神病药引起的副作用均与生活质量得分显着相关。多元回归分析表明，精神分裂症患者的主观QOL表现为抑郁症状，抗精神病药致帕金森病副作用，绝望和发病年龄是4个最强的预测指标。这些变量占该QOL模型总方差的39.2％。结论：结果表明，WHOQOL-BREF是一种用于精神分裂症患者心理评估健康问题的有前途的模型。此外，本研究结果突出了理解QOL概念复杂性质的重要性。我们的研究还支持以下观点：不同的QOL域可能具有不同的预测因素。

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