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Combined spinal and epidural anesthesia for cesarean section: a retrospective study with 0.5% hyperbaric bupivacaine

机译:腰麻与硬膜外联合麻醉用于剖宫产:0.5%高压布比卡因的回顾性研究

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BACKGROUND: We investigated retrospectively the relationship between the intrathecal dose of 0.5% hyperbaric bupivacaine and the use of 2% mepivacaine through an epidural catheter. METHODS: Forty-nine patients undergoing cesarean section with combined spinal and epidural anesthesia (CSEA) were analyzed. They were divided into two groups; with (CSEA group) and without additional epidural injection group (spinal group). RESULTS: In the CSEA group (24 patients received 1.2 +/- 0.4 ml of 0.5% hyperbaric bupivacaine), 5-10 ml of 2% mepivacaine were required to achieve the adequate surgical anesthesia. In the spinal group (25 patients received 1.6 +/- 0.3 ml of 0.5% hyperbaric bupivacaine), cesarean section was performed without additional mepivacaine before delivery. The analgesic level and the amount of fluid infusion were similar in the two groups. However, 20% of patients in the spinal group showed hypotension (systolic blood pressure below 80 mmHg), although no patients in the CSEA group developed hypotension. The amount of ephedrine used before delivery was significantly larger in the spinal group (8.9 +/- 7.7 mg) than in the CSEA group (3.9 +/- 4.3 mg). CONCLUSIONS: Spinal anesthesia induced by 1.2 ml of 0.5% hyperbaric bupivacaine with sequential epidural block induced by 5-10 ml of 2% mepivacaine caused no hypotension during cesarean section.
机译:背景:我们回顾性研究了硬膜外导管鞘内注射0.5%高压布比卡因与使用2%美比卡因之间的关系。方法:对49例行剖宫产并结合脊柱和硬膜外麻醉(CSEA)的患者进行分析。他们分为两组。有(CSEA组)且无额外硬膜外注射组(脊髓组)。结果:CSEA组(24例患者接受1.2 +/- 0.4毫升0.5%的高压布比卡因),需要5-10毫升2%的米比卡因以实现适当的手术麻醉。在脊髓组(25例患者接受1.6 +/- 0.3毫升的0.5%高压布比卡因),剖宫产在分娩前无需额外的甲哌卡因。两组的镇痛水平和输液量相似。然而,尽管CSEA组中没有患者出现低血压,但是脊柱组中20%的患者表现出低血压(收缩压低于80 mmHg)。脊髓组(8.9 +/- 7.7毫克)分娩前的麻黄碱用量明显大于CSEA组(3.9 +/- 4.3毫克)。结论:1.2 ml 0.5%的高压布比卡因引起的脊髓麻醉和5-10 ml 2%的米比卡因引起的连续硬膜外阻滞在剖宫产时未引起低血压。

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