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首页> 外文期刊>Computer Methods and Programs in Biomedicine: An International Journal Devoted to the Development, Implementation and Exchange of Computing Methodology and Software Systems in Biomedical Research and Medical Practice >Preliminary study on the accuracy of respiratory input impedance measurement using the interrupter technique.
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Preliminary study on the accuracy of respiratory input impedance measurement using the interrupter technique.

机译：使用中断器技术测量呼吸输入阻抗的准确性的初步研究。

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摘要

Respiratory input impedance contains information about the state of pulmonary mechanics in the frequency domain. In this paper the possibility of respiratory impedance measurement by interrupter technique as well as the accuracy of this approach are assessed. Transient states of flow and pressure recorded during expiratory flow interruption are simulated with a complex, linear model for the respiratory system and then used to calculate the impedance, including three states of respiratory mechanics and the influence of the measurement noise. The results of computations are compared to the known, theoretical impedance of the model. At 1 kHz sampling rate, the optimal time window lays between 100 and 200 ms and is centred around the pressure jump caused by the flow interruption. The proposed algorithm yields satisfactory accuracy in the range from 10 to 400 Hz, particularly to 150 Hz. Depending on the simulated respiratory system state, the error of calculated impedance (relative Euclidean distance between the vectors of computed and theoretical values), for the window of 190 ms, varies between 5.0% and 7.1%.
机译：呼吸输入阻抗包含有关频域中肺力学状态的信息。在本文中，评估了通过中断器技术测量呼吸阻抗的可能性以及该方法的准确性。使用复杂的线性呼吸系统模型对呼气中断期间记录的流量和压力的瞬态进行仿真，然后将其用于计算阻抗，包括呼吸力学的三种状态和测量噪声的影响。将计算结果与模型的已知理论阻抗进行比较。在1 kHz的采样率下，最佳时间窗口位于100到200 ms之间，并以流动中断引起的压力跳跃为中心。所提出的算法在10到400 Hz，特别是150 Hz范围内产生令人满意的精度。取决于模拟的呼吸系统状态，对于190毫秒的窗口，计算出的阻抗误差（计算值和理论值的向量之间的相对欧几里得距离）在5.0％和7.1％之间变化。

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