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首页> 外文期刊>Computer Methods and Programs in Biomedicine: An International Journal Devoted to the Development, Implementation and Exchange of Computing Methodology and Software Systems in Biomedical Research and Medical Practice >Diffusion and perfusion MR imaging in acute ischemic stroke: a comparison to SPECT.
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Diffusion and perfusion MR imaging in acute ischemic stroke: a comparison to SPECT.

机译：急性缺血性卒中的扩散和灌注MR成像：与SPECT的比较。

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摘要

Diffusion (DWI) and perfusion (PWI) magnetic resonance imaging are relatively new methods of clinical imaging that probably can detect infarcted (DWI) and hypoperfused but still salvageable tissue (PWI) in acute human stroke. Forty-six acute stroke patients were imaged within 24 h of ictus, on the second day and after a week. SPECT was also performed on 23 patients in the acute phase (first or second day). On the first day, mean volume of hypoperfused tissue was significantly greater (P<0.001) than the infarcted tissue. The initial hypoperfusion volume correlated significantly with the final infarct size (P<0.001). The initial perfusion-diffusion mismatch correlated significantly with the infarct growth (P< or =0.001). The hypoperfusion volumes measured from PWI and SPECT correlated significantly (P<0.001). In conclusion, combined DWI and PWI is a powerful tool in evaluating the hemodynamics of acute ischemic stroke and can predict the infarct growth during 1 week.
机译：扩散（DWI）和灌注（PWI）磁共振成像是临床成像中相对较新的方法，可以在急性人类卒中中检测出梗塞（DWI）和灌注不足但仍可抢救的组织（PWI）。在发作24小时内，第二天和一周后对46例急性中风患者进行了成像。在急性期（第一天或第二天）还对23例患者进行了SPECT。在第一天，灌注不足的组织的平均体积显着大于梗塞的组织（P <0.001）。初始灌注不足量与最终梗死面积显着相关（P <0.001）。最初的灌注-扩散失配与梗死的增长显着相关（P <或= 0.001）。从PWI和SPECT测量的灌注不足量显着相关（P <0.001）。总之，DWI和PWI结合是评估急性缺血性中风的血流动力学的有力工具，可以预测1周内梗塞的增长。

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