Development of immunopathology in patients with yersinia infection

Shestakova IV; Iushchuk ND; Andreev IV; Shepeleva GK; Popova TI

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Development of immunopathology in patients with yersinia infection

机译：耶尔森氏菌感染患者的免疫病理学发展

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AIM: To evaluate clinical significance of changes in IL-6 concentration and neopterin in peripheral blood of patients for prognosis of the course and outcome of yersinia infection (YI). MATERIAL AND METHODS: Clinical examination and laboratory tests, 1-5-year follow-up were conducted in 68 patients with a cyclic, recurrent and lingering course of the disease. IL-6 and neopterin concentrations were measured in the course of the disease. RESULTS: Dynamic control over IL-6 concentrations in the blood of patients with yersinia infection provides information predicting the disease course and prognosis. Blood concentrations of neopterin are of help in prognostication of long-term outcomes of acute infection. CONCLUSION: Pathological syndromes forming in acute stage of yersinia infection are related to interleukin-dependent immunopathology.

机译：目的：评估患者外周血IL-6浓度和新蝶呤变化对耶尔森菌感染（YI）的病程和预后的临床意义。材料与方法：对68例具有周期性，复发性和持续性病程的患者进行了临床检查和实验室测试，进行了1-5年的随访。在疾病过程中测量IL-6和新蝶呤的浓度。结果：动态控制耶尔森氏菌感染患者血液中IL-6的浓度可提供预测疾病进程和预后的信息。新蝶呤的血药浓度有助于急性感染的长期预后。结论：耶尔森氏菌感染急性期形成的病理综合征与白细胞介素依赖性免疫病理有关。

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《Терапевтичесκий архив》 |2005年第11期|共4页
作者
Shestakova IV; Iushchuk ND; Andreev IV; Shepeleva GK; Popova TI;
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正文语种 rus
中图分类诊断学;
关键词
Interleukin-6; Neopterin; Yersinia Infections; 白细胞介素6; 新蝶呤; 耶尔森氏菌感染;

机译：Interleukin-6;Neopterin;Yersinia Infections;白细胞介素6;新蝶呤;耶尔森氏菌感染;

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1. Development of immunopathology in patients with yersinia infection [J] . Shestakova IV, Iushchuk ND, Andreev IV, Терапевтичесκий архив . 2005,第11期

机译：耶尔森氏菌感染患者的免疫病理学发展
2. Development of immunopathology in patients with yersinia infection [J] . Shestakova IV, Iushchuk ND, Andreev IV, Терапевтичесκий архив . 2005,第11期

机译：yersinia感染患者免疫病理学的发展
3. Development of an LPS-based ELISA for diagnosis of Yersinia enterocolitica O:3 infections in Danish patients: a follow-up study [J] . Tine Dalby, Eva Rasmussen, Peter Schiellerup, BMC Microbiology . 2017,第1期

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机译：免疫调节诱导可防止慢性蠕虫感染和过敏症中免疫病理学的关系
5. The mechanisms and functions of the Yersinia pseudotuberculosis outer membrane adhesins invasin and YadA in phagocytic uptake and systemic infections. [D] . Hudson, Krischan Jerry. 2006

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6. Development of an LPS-based ELISA for diagnosis of Yersinia enterocolitica O:3 infections in Danish patients: a follow-up study [O] . Tine Dalby, Eva Rasmussen, Peter Schiellerup, 2017

机译：基于LPS的ELISA诊断丹麦小肠结肠炎耶尔森氏菌O：3感染的进展：一项后续研究
7. 1539. Diagnosis of Yersinia enterocolitica in Cancer Patients With Diarrhea in the Era of Molecular Diagnostics for Gastrointestinal Infections [O] . Elizabeth Wang, Micah Bhatti, Pablo Okhuysen 2018

机译：1539.诊断胃肠诊断时代腹泻患者癌症患者的鉴定癌症患者

Development of immunopathology in patients with yersinia infection

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