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Pathogenesis of IgE-mediated food allergy

机译：IgE介导的食物过敏的发病机理

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摘要

Food allergy is a prevalent disease for which there is no current treatment beyond careful food avoidance. Accidental exposure to foods causes reactions in allergic individuals that can range in severity from mild skin reactions to severe and life-threatening anaphylaxis, and there are no validated tools to predict severity of reactions. A greater understanding of the pathogenesis of food allergy is needed to develop prevention and treatment strategies for food allergy. In the last few years, there have been significant developments in the field of food allergy that have led to new ideas about food allergy prevention, diagnosis, and treatment. This review will discuss these recent advances in the food allergy field as well as identify gaps in our knowledge about the immune mechanisms of allergy and tolerance to foods.
机译：食物过敏是一种普遍的疾病，目前除了谨慎避免食物外没有其他治疗方法。意外接触食物会引起过敏性个体的反应，其严重程度从轻度皮肤反应到严重和危及生命的过敏反应，目前尚无有效的工具来预测反应的严重程度。需要对食物过敏的发病机理有更深入的了解，以制定食物过敏的预防和治疗策略。在过去的几年中，食物过敏领域出现了重大发展，从而产生了有关食物过敏预防，诊断和治疗的新思路。这篇综述将讨论食品过敏领域的这些最新进展，并找出我们在过敏免疫机制和对食品耐受性方面的知识差距。

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