• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Clinical and experimental allergy : >Quality of life in allergic rhinitis: relationship with clinical, immunological, and functional aspects.
【24h】

Quality of life in allergic rhinitis: relationship with clinical, immunological, and functional aspects.

机译：过敏性鼻炎的生活质量：与临床，免疫学和功能方面的关系。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: The relationship among nasal obstruction, T-helper type 2-dependent inflammation, nasal airflow limitation, and reversibility to the nasal decongestion test has been evidenced in allergic rhinitis (AR). Moreover, quality of life (QoL) has been widely evaluated in AR and its evaluation is considered in numerous trials. OBJECTIVE: The aim of this cross-sectional study was to identify the QoL as measured by the Quality of Life Questionnaire in a population of patients with AR and to compare it with clinical, immunological, and functional parameters. METHODS: One hundred and twenty-three patients with persistent AR were prospectively and consecutively evaluated. Clinical evaluation, skin prick test, nasal scraping for cytology, rhinomanometry, decongestion test, and QoL questionnaire were performed in all subjects. RESULTS: There was a significant relationship among QoL and functional and immunological parameters. Particularly, the multivariate analysis showed that having more than two sensitivities was a determinant of the QoL. The eosinophil count was significantly associated with QoL as well as the baseline nasal flow (mL/s) with the eye symptoms scale only. CONCLUSIONS: This study provides the first evidence that QoL in AR is strictly associated with allergic inflammation and eye symptoms significantly contribute to impairment of QoL. QoL, moreover, represents an important aspect to consider in managing patients with AR as it has a relationship with clinical, immunological, and functional parameters.
机译：背景：在过敏性鼻炎（AR）中，已经证明了鼻阻塞，T型辅助2型炎症，鼻气流受限和鼻充血试验可逆性之间的关系。此外，生活质量（QoL）已在AR中得到广泛评估，并且其评估已在众多试验中得到考虑。目的：这项横断面研究的目的是鉴定生活质量调查表（ARQ）对AR患者的生活质量，并将其与临床，免疫学和功能参数进行比较。方法：对123例持续性AR患者进行前瞻性和连续评估。在所有受试者中进行了临床评估，皮肤点刺试验，细胞学鼻刮擦，鼻测压，充血试验和QoL问卷。结果：QoL与功能和免疫学参数之间存在显着关系。特别是，多变量分析表明，具有两种以上的敏感性是QoL的决定因素。嗜酸性粒细胞计数与QoL以及基线鼻流量（mL / s）仅与眼睛症状量表显着相关。结论：这项研究提供了第一个证据，即AR中的QoL与过敏性炎症严格相关，并且眼部症状明显导致了QoL的损害。此外，QoL代表了在管理AR患者时要考虑的重要方面，因为它与临床，免疫学和功能参数有关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号