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Quality-of-life assessment in Chinese families with food-allergic children.

机译：有食物过敏儿童的中国家庭的生活质量评估。

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BACKGROUND: Caucasian families with food-allergic children have a compromised quality of life (QoL) for fear of life-threatening food reactions. Such data are limited in Asian children. Based on our recent questionnaire-based survey, 8.1% of young children recruited from local nurseries and kindergartens had parent-reported adverse food reactions (AFRs). OBJECTIVE: This study tested the robustness of the Chinese Food Allergy Quality of Life-Parental Burden questionnaire (FAQL-PB) and assessed QoL in families with childhood AFR. The correlations among FAQL-PB items were evaluated by factor analysis. METHODS: Two hundred and ninety-eight of 3677 children aged 2-7 years had parent-reported AFR, and 197 (66.1%) of them completed the 17 items of our self-administered FAQL-PB. Six hundred and thirty-nine (18.9%) children without AFR returned this questionnaire. Factor analysis was used to delineate the inter-relationship among the FAQL-PB items. RESULTS: Cronbach alpha for our Chinese FAQL-PB was 0.976, and the median (interquartile range) FAQL-PB scores of children with and without parent-reported AFR were 0.10 (0.02-0.32) and 0 (0-0.18), respectively (P < 0.001). Factor analysis confirmed excellent correlations between FAQL-PB items. The 17 items were clustered into two factors, which explained 79.7% of the total variance. Among children with AFR, FAQL-PB scores increased with increasing numbers of foods that caused AFRs (P < 0.001 for trend). Thirty (15.2%) children had impaired QoL, defined as average item FAQL-PB score > or = 0.5. Impaired QoL was associated with AFR that was caused by >3 foods (P = 0.001), current food avoidance (P = 0.005) and AFR caused by peanut (P = 0.003), egg (P = 0.011) and cow's milk (P = 0.028), and current flexural dermatitis (P = 0.011). CONCLUSIONS: FAQL-PB is a robust measure of AFR-specific parental QoL, which is impaired in Chinese children with parent-reported AFR. Flexural dermatitis, current food avoidance and AFR caused by multiple foods are independent risk factors for lower parental QoL.
机译：背景：患有食物过敏儿童的白种人家庭的生活质量（QoL）有所下降，因为他们担心会威胁生命的食物反应。在亚洲儿童中，此类数据有限。根据我们最近基于问卷调查的调查，从当地托儿所和幼儿园招募的幼儿中有8.1％的家长报告了不良食物反应（AFR）。目的：本研究测试了中国食物过敏性生活质量父母亲负担量问卷（FAQL-PB）的稳健性，并评估了儿童AFR家庭的QoL。 FAQL-PB项目之间的相关性通过因素分析进行​​评估。方法：2677岁的3677名儿童中有298名有父母报告的AFR，其中197名（66.1％）完成了我们自行管理的FAQL-PB的17项。 639名（18.9％）没有AFR的儿童返回了此问卷。因子分析用于描述FAQL-PB项目之间的相互关系。结果：我们的中文FAQL-PB的Cronbach alpha为0.976，有和没有父母报告的AFR的儿童的中位数（四分位数范围）FAQL-PB分数分别为0.10（0.02-0.32）和0（0-0.18）（ P <0.001）。因子分析证实了FAQL-PB项目之间的良好相关性。这17个项目分为两个因素，占总方差的79.7％。在患有AFR的儿童中，FAQL-PB分数随着引起AFR的食物数量的增加而增加（趋势P <0.001）。 30（15.2％）名儿童的QoL受损，定义为FAQL-PB平均项目得分>或= 0.5。 QoL受损与> 3种食物（P = 0.001），当前避免食用（P = 0.005）和花生（P = 0.003），鸡蛋（P = 0.011）和牛奶（P = 0.028）和当前的弯曲性皮炎（P = 0.011）。结论：FAQL-PB是一种针对AFR特定的父母QoL的有效指标，在有父母报告AFR的中国儿童中受损。弯曲性皮炎，当前避免食用食物和多种食物引起的AFR是降低父母QoL的独立危险因素。

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