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Probiotics, prebiotics and synbiotics: a hope or hype in allergy?

机译:益生菌,益生元和合生元:过敏的希望还是炒作?

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摘要

In his landmark paper David Strachan demonstrated an association of hayfever with family size and position in the household in childhood. He suggested that declining family size, improvements in household facilities and in personal hygiene have reduced infection burden among families resulting in more widespread expression of atopic disease [1]. Thereafter vigorous epidemiological, clinical and experimental research emerged that has led to a revision of the original hygiene hypothesis.
机译:大卫·斯特拉坎(David Strachan)在他的地标性论文中证明了花粉症与家庭规模以及儿童时期在家庭中的地位有关。他认为家庭规模的缩小,家庭设施的改善和个人卫生的改善降低了家庭之间的感染负担,导致特应性疾病的广泛传播[1]。此后,出现了活跃的流行病学,临床和实验研究,从而导致对原始卫生假说的修正。

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