Sublingual immunotherapy affects transforming growth factor-beta and nasal eosinophils.

Ciprandi G; Tosca MA

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Sublingual immunotherapy affects transforming growth factor-beta and nasal eosinophils.

机译：舌下免疫疗法影响转化生长因子-β和鼻嗜酸性粒细胞。

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This article is very interesting as the authors provided the evidence that sublingual immunotherapy (SLIT) for grass pollen is able to increase sublingual Foxp3-expressing cells and allergen-specific IgG4 and IgA production [1]. This elegant study, moreover, underlines the SLIT ability to modulate local Treg function and allergen-specific immunoglobulin production pattern. On the other hand, it is well known that Durham's group is performing several studies that successfully tried to clarify the mechanism of action of allergen-specific immunotherapy.

机译：本文非常有趣，因为作者提供了草粉花粉的舌下免疫疗法（SLIT）能够增加舌下Foxp3表达细胞和过敏原特异性IgG4和IgA产生的证据[1]。此外，这项出色的研究强调了SLIT能够调节局部Treg功能和过敏原特异性免疫球蛋白的产生方式。另一方面，众所周知，达勒姆（Durham）小组正在进行多项研究，成功地阐明了过敏原特异性免疫疗法的作用机理。

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《Clinical and experimental allergy :》 |2010年第9期|共2页
作者
Ciprandi G; Tosca MA;
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正文语种 eng
中图分类医学免疫学;
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1. Sublingual immunotherapy affects transforming growth factor-beta and nasal eosinophils. [J] . Ciprandi G, Tosca MA Clinical and experimental allergy : . 2010,第9期

机译：舌下免疫疗法影响转化生长因子-β和鼻嗜酸性粒细胞。
2. Progranulin Promotes Bleomycin-Induced Skin Sclerosis by Enhancing Transforming Growth Factor-beta/Smad3 Signaling through Up-Regulation of Transforming Growth Factor-beta Type I Receptor [J] . Yang Ting, Zhang Xuemei, Chen Aijun, American Journal of Pathology: Official Publication of the American Association of Pathologists . 2019,第8期

机译：通过提高转化生长因子-βα型受体的上调，通过增强转化生长因子-β-β/ smad3信号传导来促进博尔霉素诱导的皮肤硬化。
3. Distinct roles of transforming growth factor-beta signaling and transforming growth factor-beta receptor inhibitor SB431542 in the regulation of p21 expression [J] . Koo Bon-Hun, Kim Yeaji, Cho Yang Je, European Journal of Pharmacology: An International Journal . 2015,第Null期

机译：转化生长因子-β信号转导和转化生长因子-β受体抑制剂SB431542在调节p21表达中的不同作用
4. Transforming growth factor-beta inhibits the expression of clock genes [C] . Heidemarie Gast, Sonja Gordic, Saskia Petrzilka, International Society for Neuroimmunomodulation . 2012

机译：转化生长因子-β抑制时钟基因的表达
5. Transforming growth factor-beta1 activation and transforming growth factor-beta receptor 2 expression levels in the regulation of the TGF-beta signaling pathway. [D] . Rojas, Andres. 2008

机译：在调节TGF-beta信号通路中转化生长因子-beta1激活和转化生长因子-beta受体2的表达水平。
6. Type I (RI) and type II (RII) receptors for transforming growth factor-beta isoforms are expressed subsequent to transforming growth factor-beta ligands during excisional wound repair. [O] . L. I. Gold, J. J. Sung, J. W. Siebert, 1997

机译：在切除伤口修复过程中在转化生长因子-β配体之后表达用于转化生长因子-β亚型的I型（RI）和II型（RII）受体。
7. Characterization of a 60-kDa cell surface-associated transforming growth factor-beta binding protein that can interfere with transforming growth factor-beta receptor binding [O] . Piek E., Franzén P., Heldin C-H., 1997

机译：60 kDa细胞表面相关的转化生长因子-β结合蛋白的表征，该蛋白可干扰转化生长因子-β受体的结合
8. Initial Biochemical Characterization of Cells Derived from Human Periodontium and Their In vitro Response to Platelet-Derived Growth Factor, Epidermal Growth Factor and Transforming Growth Factor-Beta [R] . Piche', J. E. 1988

机译：人牙周组织细胞的初步生化特征及其对血小板衍生生长因子，表皮生长因子和转化生长因子-β的体外反应

Sublingual immunotherapy affects transforming growth factor-beta and nasal eosinophils.

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