Lurasidone for the treatment of depressive symptoms in schizophrenia: analysis of 4 pooled, 6-week, placebo-controlled studies

Nasrallah Henry A.; Cucchiaro Josephine B.; Mao Yongcai; Pikalov Andrei A.; Loebel Antony D.

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Lurasidone for the treatment of depressive symptoms in schizophrenia: analysis of 4 pooled, 6-week, placebo-controlled studies

机译：卢拉西酮治疗精神分裂症的抑郁症状：对4项汇总，为期6周的安慰剂对照研究的分析

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Objective. Depressive symptoms are common in schizophrenia and can worsen outcomes and increase suicide risk. Lurasidone is an atypical antipsychotic agent indicated for the treatment of schizophrenia and for the treatment of major depressive episodes associated with bipolar I disorder. This post hoc analysis evaluated the effect of lurasidone on depressive symptoms in patients with schizophrenia.

机译：目的。抑郁症状在精神分裂症中很常见，会恶化结局并增加自杀风险。卢拉西酮是一种非典型的抗精神病药，适用于精神分裂症的治疗以及与双相性I型障碍相关的主要抑郁发作的治疗。事后分析评估了卢拉西酮对精神分裂症患者抑郁症状的影响。

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《CNS spectrums》 |2015年第2期|共8页
作者
Nasrallah Henry A.; Cucchiaro Josephine B.; Mao Yongcai; Pikalov Andrei A.; Loebel Antony D.;
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正文语种 eng
中图分类神经病学与精神病学;
关键词
Atypical antipsychotic; depression; depressive symptom; lurasidone; schizophrenia;

机译：非典型抗精神病药;抑郁症;抑郁症状;卢拉西酮;精神分裂症;

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1. Lurasidone for the treatment of depressive symptoms in schizophrenia: analysis of 4 pooled, 6-week, placebo-controlled studies [J] . Nasrallah Henry A., Cucchiaro Josephine B., Mao Yongcai, CNS spectrums . 2015,第2期

机译：卢拉西酮治疗精神分裂症的抑郁症状：对4项汇总，为期6周的安慰剂对照研究的分析
2. Efficacy of lurasidone across five symptom dimensions of schizophrenia: Pooled analysis of short-term, placebo-controlled studies [J] . Loebel A., Cucchiaro J., Silva R., European psychiatry: the journal of the Association of European Psychiatrists . 2015,第1期

机译：卢拉西酮对精神分裂症五个症状维度的功效：短期，安慰剂对照研究的汇总分析
3. Lurasidone for the treatment of acutely psychotic patients with schizophrenia: A 6-week, randomized, placebo-controlled study [J] . NasrallahH.A., SilvaR., PhillipsD., Journal of psychiatric research . 2013,第5期

机译：卢拉西酮治疗急性精神病性精神分裂症的患者：一项为期六周的随机安慰剂对照研究
4. Effects of Occupational Stressors on Depressive Symptoms: Longitudinal Study Among Medical Services and Welfare Workers [C] . Takumi Iwaasa, Takeshi Sasaki, Toru Yoshikawa, Virtual Conference on Physical Ergonomics and Human Factors;Virtual Conference on Social Occupational Ergonomics;Virtual Conference on Cross-Cultural Decision Making;International Conference on Applied Human Factors and Ergonomics . 2020

机译：职业压力源对抑郁症状的影响：医疗服务与福利工作者的纵向研究
5. The impact of efficacious treatments for major depressive disorder on remission rates of specific symptoms: A re-analysis of the Treatment of Depression Collaborative Research Program. [D] . Stewart, Jeremy Gordon. 2009

机译：有效治疗重度抑郁症对特定症状缓解率的影响：《抑郁症治疗合作研究计划》的重新分析。
6. Lurasidone for the treatment of depressive symptoms in schizophrenia: analysis of 4 pooled 6-week placebo-controlled studies [O] . Henry A. Nasrallah, Josephine B. Cucchiaro, Yongcai Mao, -1

机译：卢拉西酮治疗精神分裂症的抑郁症状：对4项汇总为期6周的安慰剂对照研究的分析
7. Efficacy and safety of lurasidone in adolescents and young adults with schizophrenia: A pooled post hoc analysis of double-blind, placebo-controlled 6-week studies [O] . Isabella Costamagna, Fabrizio Calisti, Agnese Cattaneo, 2021

机译：LuRasidone在青少年和青少年与精神分裂症的疗效和安全性：双盲，安慰剂控制6周研究的汇集后HOC分析

Lurasidone for the treatment of depressive symptoms in schizophrenia: analysis of 4 pooled, 6-week, placebo-controlled studies

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