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首页> 外文期刊>Contact dermatitis >Contact sensitization to tree moss (Evernia furfuracea extract, INCI) is heterogeneous
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Contact sensitization to tree moss (Evernia furfuracea extract, INCI) is heterogeneous

机译：对树木苔藓的接触敏化（Evernia furfuracea提取物，INCI）是异质的

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Background. Evernia prunastri (oak moss) and Evernia furfuracea (tree moss) are lichens from which natural extracts are obtained. Objectives. To identify possible subgroups of E. furfuracea-sensitized patients according to whether these are allergic to lichen components or to contaminants. Methods. A retrospective analysis was performed of surveillance data collected by the Information Network of Departments of Dermatology () in 2003-2010 with oak moss absolute (1% pet.), tree moss absolute (1% pet.), and colophonium (colophony, 20% pet.). Results. In total, 3030 patients had been tested with all three allergens. Positive reactions to E. furfuracea were observed in 6.37%, to E. prunastri in 5.71%, and to colophonium in 4.82%. Concordance between positive reactions to E. prunastri and E. furfuracea was good only in patients not co-sensitized to colophonium (Cohen's ? = 0.681, 95% confidence interval 0.615-0.746). Moreover, E. furfuracea-sensitized patients showed (strong or extreme) concomitant reactions to colophonium significantly more often if not co-sensitized to E. prunastri. Conclusions. Two subgroups of E. furfuracea-sensitized patients are identifiable: (i) those with sensitization to (oxidized) resin acids, as indicated by positive patch test reactions also to colophonium, and (ii) those non-sensitized to resin acids, but sensitized to common constituents of E. prunastri and E. furfuracea.
机译：背景。 Evernia prunastri（橡苔）和Evernia furfuracea（树苔）是从中提取天然提取物的地衣。目标。根据是否对地衣芽孢杆菌成分或污染物过敏，来识别呋喃呋喃菌敏感的亚组。方法。对由皮肤科信息网络（）在2003-2010年收集的监测数据进行了回顾性分析，其中橡苔绝对含量（1％宠物），树苔绝对含量（1％宠物）和col叶（colophony，20 ％ 宠物。）。结果。总共有3030名患者接受了所有三种过敏原的检测。观察到对糠fu肠球菌的阳性反应为6.37％，对李子肠球菌的阳性反应为5.71％，而对苯乙铵的阳性反应为4.82％。仅对未对col碱共敏的患者，对普纳氏肠杆菌和糠fu肠杆菌的阳性反应之间的一致性良好（Cohen's = 0.681，95％置信区间0.615-0.746）。而且，如果不对普纳氏肠杆菌同时过敏，那么对糠醛肠球菌致敏的患者表现出（强烈或极度）对蛇毒的伴随反应明显更多。结论可以鉴定出糠fur肠球菌致敏患者的两个亚组：（i）对（氧化的）树脂酸致敏的患者，如对斑oph试验也呈阳性的斑贴试验反应表明;（ii）对树脂酸不敏但致敏的患者普里氏大肠杆菌和糠fu大肠杆菌的常见成分。

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