High Resolution Structural Analyses of Mutant Chitinase A Complexes with Substrates Provide New Insight into the Mechanism of Catalysis

Yannis Papanikolau; Gali Prag; Giorgos Tavlas

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High Resolution Structural Analyses of Mutant Chitinase A Complexes with Substrates Provide New Insight into the Mechanism of Catalysis

机译：带有基质的突变型几丁质酶A复合物的高分辨率结构分析为催化机理提供了新的见解

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Chitinase A (ChiA) from the bacterium Seratia marcescens is a hydrolytic enzyme, which cleaves #beta#-1,4-glycosidic bonds of the natural biopolymer chitin to generate di-N-acetyl-chitobiose.

机译：来自粘质沙雷氏菌的几丁质酶A（ChiA）是一种水解酶，可切割天然生物聚合物几丁质的＃beta＃-1,4-糖苷键，生成二-N-乙酰基-壳二糖。

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《Biochemistry》 |2001年第38期|共6页
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Yannis Papanikolau; Gali Prag; Giorgos Tavlas;
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1. High Resolution Structural Analyses of Mutant Chitinase A Complexes with Substrates Provide New Insight into the Mechanism of Catalysis [J] . Yannis Papanikolau, Gali Prag, Giorgos Tavlas Biochemistry . 2001,第38期

机译：带有基质的突变型几丁质酶A复合物的高分辨率结构分析为催化机理提供了新的见解
2. Structural studies of duck δ2 crystallin mutants provide insight into the role of Thr161 and the 280s loop in catalysis [J] . Cathy HORVATIN, G.?David SMITH, Liliana?M. SAMPALEANU, The biochemical journal . 2004,第2期

机译：鸭δ2晶体蛋白突变体的结构研究提供了对Thr161和280s环在催化中的作用的深入了解
3. Structural studies of duck delta 2 crystallin mutants provide insight into the role of Thr(161) and the 280s loop in catalysis [J] . Sampaleanu LM, Codding PW, Lobsanov YD, The Biochemical Journal . 2004,第Pta2期

机译：鸭delta 2 crystallin突变体的结构研究提供了深入了解Thr（161）和280s环在催化中的作用
4. New Catalysts May Provide Insights into Role of Nonframework Alumina in Catalytic Cracking Catalysis [C] . Richard W. Fowler, Ruizhong Hu the International Symposium on Advances in Fluid Cracking Catalysts . 2004

机译：新的催化剂可以在催化裂化催化催化裂解中的非框架氧化铝的作用提供洞察力
5. Chelation-enforced metal-arene interactions: Insights into substrate binding and catalysis by late transition metal complexes. [D] . Lin, Sibo. 2014

机译：螯合增强的金属-芳烃相互作用：后期过渡金属络合物对底物结合和催化的见解。
6. Structural studies of duck δ2 crystallin mutants provide insight into the role of Thr161 and the 280s loop in catalysis [O] . Liliana M. Sampaleanu, Penelope W. Codding, Yuri D. Lobsanov, 2004

机译：鸭δ2晶状蛋白突变体的结构研究可深入了解Thr161和280s环在催化中的作用
7. Modeled ligand-protein complexes elucidate the origin of substrate specificity and provide insight into catalytic mechanisms of phenylalanine hydroxylase and tyrosine hydroxylase [O] . Maaß A., Scholz J., Moser A. 2003

机译：模拟的配体 - 蛋白质复合物阐明了底物特异性的起源，并提供了对苯丙氨酸羟化酶和酪氨酸羟化酶催化机制的深入了解。

High Resolution Structural Analyses of Mutant Chitinase A Complexes with Substrates Provide New Insight into the Mechanism of Catalysis

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