Membrane Binding Kinetics of Protein Kinase C #beta#II Mediated by the C2 Domain

Eric A. Nalefski; Alexandra C. Newton

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Membrane Binding Kinetics of Protein Kinase C #beta#II Mediated by the C2 Domain

机译：C2域介导的蛋白激酶C＃beta＃II的膜结合动力学。

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Conventional isoforms of proteinkinase C (PKC) are activated when their two membranetargeting modeules, the C1 and C2 domains, bind the second messengers diacylglycerol (DG) and Ca~(2+), respectively.

机译：当它们的两个膜靶向模块C1和C2域分别结合第二信使二酰基甘油（DG）和Ca〜（2+）时，蛋白激酶C（PKC）的常规同工型被激活。

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《Biochemistry》 |2001年第44期|共14页
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Eric A. Nalefski; Alexandra C. Newton;
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1. Membrane Binding Kinetics of Protein Kinase C #beta#II Mediated by the C2 Domain [J] . Eric A. Nalefski, Alexandra C. Newton Biochemistry . 2001,第44期

机译：C2域介导的蛋白激酶C＃beta＃II的膜结合动力学。
2. Electrostatic and Hydrophobic Interactions Differentially Tune Membrane Binding Kinetics of the C2 Domain of Protein Kinase Cα [J] . Angela Scott, Corina Antal, Alexandra Newton The Journal of biological chemistry . 2013,第23期

机译：静电和疏水相互作用蛋白激酶Cα的C2结构域的差异曲调膜结合动力学
3. The C2 domain of protein kinase Cα is directly involved in the diacylglycerol-dependent binding of the C1 domain to the membrane [J] . Pablo Conesa-Zamora, Juan C. Gomez-Fernandez, Senena Corbalan-Garcia Biochimica et Biophysica Acta. Molecular and cell biology of Lipids . 2000,第2a3期

机译：蛋白激酶Cα的C2结构域直接参与C1结构域与膜的二酰基甘油依赖性结合
4. Differences in structural dynamics of Factor VIII and Lactadherin C2 domains in relation to membrane binding employing DXMS analysis. [C] . Dennis P. Pantazatos, Chris Gessner, G. E. Gilbert, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2009

机译：与膜结合的因子VIII和乳酸素C2结构域的结构动态的差异与DXMS分析相关。
5. Calcium activation and membrane docking of C2 domains for conventional isoforms of protein kinase C. [D] . Kohout, Susy Carolina. 2002

机译：钙激活和C2域的膜对接，用于蛋白激酶C的常规同工型。
6. Electrostatic and Hydrophobic Interactions Differentially Tune Membrane Binding Kinetics of the C2 Domain of Protein Kinase Cα [O] . Angela M. Scott, Corina E. Antal, Alexandra C. Newton 2013

机译：静电和疏水相互作用微分调节蛋白激酶CαC2域的膜结合动力学。
7. Electrostatic and Hydrophobic Interactions Differentially Tune Membrane Binding Kinetics of the C2 Domain of Protein Kinase Cα [O] . Angela M. Scott, Corina E. Antal, Alexandra C. Newton 2013

机译：静电和疏水相互作用蛋白激酶Cα的C2结构域的差异曲调膜结合动力学

Membrane Binding Kinetics of Protein Kinase C #beta#II Mediated by the C2 Domain

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