Probing the Importance of the Amino-Terminal Sequence of the #beta#- and #gamma#-Chains to the Properties of Normal Adult and Fetal Hemoglobins

Ching-Hsuan Tsai; Sandra C. Larso; Tong-Jian Shen

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Probing the Importance of the Amino-Terminal Sequence of the #beta#- and #gamma#-Chains to the Properties of Normal Adult and Fetal Hemoglobins

机译：探讨＃beta＃-和＃gamma＃-链的氨基末端序列对正常成人和胎儿血红蛋白特性的重要性

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A recombinant mutant of human fetal hemoglobin (Hb F), named rHb oScar, has been cpmstricted tp explore the importance of the sequence of the amino-terminal region of the #gamma3-chain to the structural and functional properties of Hb F as compared to human normal adult hemoglobin (Hb A).

机译：有人限制了人类胎儿血红蛋白（Hb F）的重组突变体rHb oScar的表达，探索了＃gamma3链氨基末端区域序列对Hb F的结构和功能特性的重要性。人类正常成人血红蛋白（Hb A）。

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《Biochemistry》 |2001年第40期|共9页
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Ching-Hsuan Tsai; Sandra C. Larso; Tong-Jian Shen;
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1. Probing the Importance of the Amino-Terminal Sequence of the #beta#- and #gamma#-Chains to the Properties of Normal Adult and Fetal Hemoglobins [J] . Ching-Hsuan Tsai, Sandra C. Larso, Tong-Jian Shen Biochemistry . 2001,第40期

机译：探讨＃beta＃-和＃gamma＃-链的氨基末端序列对正常成人和胎儿血红蛋白特性的重要性
2. Transposing sequences between fetal and adult hemoglobins indicates which subunits and regulatory molecule interfaces are functionally related. [J] . Chen W, Dumoulin A, Li X, Biochemistry . 2000,第13期

机译：胎儿和成人血红蛋白之间的转座序列表明哪些亚基和调节分子界面在功能上相关。
3. PRODUCTION OF HUMAN NORMAL ADULT AND FETAL HEMOGLOBINS IN ESCHERICHIA COLI [J] . Shen TJ., Zou M., Sun DP., Protein Engineering . 1997,第9期

机译：大肠杆菌中人类正常成人和胎儿血红蛋白的产生
4. Synthesis and characterization of the photophysical and photochemical properties of sequence specific DNA -binding probes. [D] . Thompson, Martin J. 2000

机译：序列特异性DNA结合探针的光物理和光化学特性的合成与表征。
5. The effects of deoxygenation of adult and fetal hemoglobin on the synthesis of red cell 23-diphosphoglycerate and its in vivo consequences [O] . Frank A. Oski, Arlan J. Gottlieb, William W. Miller, 1970

机译：成年和胎儿血红蛋白脱氧对23-二磷酸甘油红细胞合成的影响及其体内影响
6. Fetal hemoglobin-containing cells have the same mean corpuscular hemoglobin as cells without fetal hemoglobin: a reciprocal relationship between gamma- and beta-globin gene expression in normal subjects and in those with high fetal hemoglobin production [O] . GJ Dover, SH Boyer 1987

机译：含胎儿血红蛋白的细胞具有与没有胎儿血红蛋白的细胞相同的平均碎石血红蛋白：正常受试者和胎儿血红蛋白产生高的γ-和β-珠蛋白基因表达之间的往复关系
7. Probing the Interstellar Medium Properties in a Morphologically Diverse Sample of Normal Galaxies [R] . Lord, S., Dinerstein, H., Shirley, Y., 1999

机译：探讨正常星系形态多样性中的星际介质特征

Probing the Importance of the Amino-Terminal Sequence of the #beta#- and #gamma#-Chains to the Properties of Normal Adult and Fetal Hemoglobins

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