Synthesis, in vitro and in vivo studies of Gd-DTPA-XDA-D1-Glc(OH) complex as a new potential MRI contrast agent.

Ozaki N; Sankar AU; Yamashita

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Synthesis, in vitro and in vivo studies of Gd-DTPA-XDA-D1-Glc(OH) complex as a new potential MRI contrast agent.

机译：Gd-DTPA-XDA-D1-Glc（OH）复合物作为一种新型的潜在MRI造影剂的合成，体外和体内研究。

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A new type of dendritic molecules Gd-DTPA-XDA-D1-Glc(OH), which work as a functionalized ligand coordinating gadolinium(III) ion at the center of their frameworks with two glucose moieties on the molecular surfaces, were readily synthesized with high yield. The structures were established by IR, (1)H, (13)C NMR, and mass spectral studies. Its bio-distribution patterns were evaluated on rats.

机译：新型的树枝状分子Gd-DTPA-XDA-D1-Glc（OH）可以作为功能化的配体，在其骨架中心与分子表面上的两个葡萄糖部分配位g（III）离子高产。通过IR，（1）H，（13）C NMR和质谱研究确定结构。在大鼠上评估了其生物分布模式。

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《Bioorganic and Medicinal Chemistry Letters》 |2010年第3期|共3页
作者
Ozaki N; Sankar AU; Yamashita;
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1. Synthesis, in vitro and in vivo studies of Gd-DTPA-XDA-D1-Glc(OH) complex as a new potential MRI contrast agent. [J] . Ozaki N, Sankar AU, Yamashita Bioorganic and Medicinal Chemistry Letters . 2010,第3期

机译：Gd-DTPA-XDA-D1-Glc（OH）复合物作为一种新型的潜在MRI造影剂的合成，体外和体内研究。
2. A Facile Synthesis, In vitro and In vivo MR Studies of D-Glucuronic Acid-Coated Ultrasmall Ln2o3 (Ln = Eu, Gd, Dy, Ho, and Er) Nanoparticles as a New Potential MRI Contrast Agent [J] . Krishna Kattel, Ja Young Park, Wenlong Xu ACS applied materials & interfaces . 2011,第9期

机译：D-葡萄糖醛酸涂层超小Ln2o3（Ln = Eu，Gd，Dy，Ho和Er）纳米粒子作为新型潜在MRI造影剂的简便合成，体外和体内MR研究
3. In vitro characterization of an Fe(8) cluster as potential MRI contrast agent. [J] . Rodriguez E, Roig A, Molins E, NMR in biomedicine . 2005,第5期

机译：Fe（8）群集作为潜在的MRI造影剂的体外表征。
4. In Vitro and In Vivo Studies Glycosylated Gadolinum Nanomagnetic Particleas (GD-DTPA-DG) as New Potential Metabolic Contrast Agent in MMRI [C] . S. Heydarnezhadi, N. Riyahi-Alam, S. Haghgoo World Congress on Medical Physics and Biomedical Engineering . 2015

机译：体外和体内研究糖基化的钆纳米磁性蛋白酶（Gd-DTPA-DG）作为MMRI的新潜在代谢造影剂
5. Practicum Three, August 2000. Novel applications of carbon-13 indirect detection NMR to metabolic tracer studies in small tissue samples. Practicum Two, December 1998. Proton and platinum-195 NMR spectroscopic characterization of the products formed in reactions of N-isobutyramide-Gly-Phe-Leu-Gly-ethylenediamine and similar model ligands with potassium tetrachloroplatinate (II). Practicum One, August 1997. Synthesis of a polyamide containing repeating macrocyclic chelate units: Evaluation of its gadolinium(3+) complex as a MRI contrast agent. [D] . Burgess, Shawn C. 2000

机译：实习三，2000年8月。Carbon-13间接检测NMR在小组织样品中代谢示踪剂研究中的新应用。实习二，1998年12月。在N-异丁酰胺-Gly-Phe-Leu-Gly-乙二胺和类似的模型配体与四氯铂酸钾（II）反应中形成的产物的质子和铂195 NMR光谱表征。实习生一，1997年8月。包含重复的大环螯合单元的聚酰胺的合成：g（3+）复合物作为MRI造影剂的评估。
6. Synthesis of nanoparticle CT contrast agents: in vitro and in vivo studies [O] . Sung June Kim, Wenlong Xu, Md Wasi Ahmad, 2015

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7. Gd(III)-EPTPAC16, a new self-assembling potential liver MRI contrast agent: in vitro characterization and in vivo animal imaging studies [O] . García-Martín, María L., Rodrigues, Tiago B., López-Larrubia, Pilar, 2013

机译：Gd（III）-EPTPAC16，一种新型的自组装潜在肝脏MRI造影剂：体外表征和体内动物成像研究
8. Poly (L-Glutamic Acid) Paramagnetic Material Complex and Use as a Biodegradable MRI Contrast Agent. [R] . Li, C., Wen, X., Jackson, E. F., 2004

机译：聚（L-谷氨酸）顺磁性材料复合物和用作可生物降解的mRI造影剂。

Synthesis, in vitro and in vivo studies of Gd-DTPA-XDA-D1-Glc(OH) complex as a new potential MRI contrast agent.

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