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Patterns of phosphorylated tyrosine hydroxylase vary with song production in female starlings

机译:雌性八哥中磷酸化酪氨酸羟化酶的模式随歌曲产生而变化

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Vocal signal production in male songbirds is well studied, but the neural correlates of female song production are poorly understood. In European starlings, females sing to defend nesting resources, and song can be considered agonistically motivated. Across vertebrates catecholamines strongly influence motivated, agonistic social behaviors. The present study was designed to provide insight into a possible role for catecholamine activity in territorial song in female starlings. We presented females that were defending nest-cavities with an unfamiliar female and assessed song production. We then measured immunolabeling for phosphorylated tyrosine hydroxylase (pTH-ir), the rate-limiting enzyme for catecholamine synthesis, in brain regions in which catecholamines stimulate agonistic behavior. Females that sang had higher pTH-ir in the caudomedial ventral tegmental area and the lateral septum than females that did not sing. Furthermore, the number of songs produced correlated positively with pTH-ir in the medial preoptic nucleus. Phosphorylation of TH is thought to occur after catecholamine release, so these results link increased catecholamine activity in several brain regions governing agonistic behavior to territorial song production in females.
机译:对雄性鸣鸟的声音信号产生进行了很好的研究,但对雌性鸣音产生的神经相关性知之甚少。在欧洲star鸟中,雌性唱歌以捍卫巢穴资源,而歌声则被认为是激动性的。在整个脊椎动物中,儿茶酚胺强烈影响着主动的,激动的社交行为。本研究旨在提供洞察力儿茶酚胺活性在女性star鸟的领土歌曲中的作用。我们介绍了与陌生的雌性一起捍卫巢穴的雌性,并评估了歌曲的产生。然后,我们在儿茶酚胺刺激激动的大脑区域中测量了磷酸化酪氨酸羟化酶(pTH-ir)(儿茶酚胺合成的限速酶)的免疫标记。唱歌的女性在腹内侧腹盖区和外侧隔中的pTH-ir高于未唱歌的女性。此外,产生的歌曲数量与内侧视前核中的pTH-ir正相关。 TH的磷酸化被认为是在释放儿茶酚胺后发生的,因此这些结果将儿茶酚胺在某些大脑区域的活动增加,从而控制了激动行为与女性的领土歌唱。

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