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首页> 外文期刊>Brain research >Monkey's short-term auditory memory nearly abolished by combined removal of the rostral superior temporal gyrus and rhinal cortices
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Monkey's short-term auditory memory nearly abolished by combined removal of the rostral superior temporal gyrus and rhinal cortices

机译:猴子的短期听觉记忆几乎被鼻尖上颞回和鼻皮质的联合切除所消除

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While monkeys easily acquire the rules for performing visual and tactile delayed matching-to-sample, a method for testing recognition memory, they have extraordinary difficulty acquiring a similar rule in audition. Another striking difference between the modalities is that whereas bilateral ablation of the rhinal cortex (RhC) leads to profound impairment in visual and tactile recognition, the same lesion has no detectable effect on auditory recognition memory (Fritz et al., 2005). In our previous study, a mild impairment in auditory memory was obtained following bilateral ablation of the entire medial temporal lobe (MTL), including the RhC, and an equally mild effect was observed after bilateral ablation of the auditory cortical areas in the rostral superior temporal gyms (rSTG). In order to test the hypothesis that each of these mild impairments was due to partial disconnection of acoustic input to a common target (e.g., the ventromedial prefrontal cortex), in the current study we examined the effects of a more complete auditory disconnection of this common target by combining the removals of both the rSTG and the MTL. We found that the combined lesion led to forgetting thresholds (performance at 75% accuracy) that fell precipitously from the normal retention duration of similar to 30 to 40 s to a duration of similar to 1 to 2 s, thus nearly abolishing auditory recognition memory, and leaving behind only a residual echoic memory. This article is part of a Special Issue entitled SI: Auditory working memory. Published by Elsevier B.V. This is an open access article under the CC BY license
机译:尽管猴子很容易获得执行视觉和触觉延迟采样匹配的规则,这是一种测试识别记忆的方法,但它们在试听中很难获得类似的规则。两种方式之间的另一个显着差异是,尽管双侧消融鼻皮质(RhC)会导致视觉和触觉识别的严重损害,但同一病变对听觉识别记忆却没有可检测的影响(Fritz et al。,2005)。在我们先前的研究中,双侧消融包括RhC在内的整个内侧颞叶(MTL)后,听觉记忆得到了轻度损害,双侧消融了在颞侧上颞叶的听觉皮质区域后,观察到了同样轻微的影响体育馆(rSTG)。为了检验以下假设:这些轻度损伤中的每一个都是由于声输入与共同目标(例如腹侧前额叶皮层)的部分断开而引起的,在本研究中,我们研究了这种完全闭合的听觉断开的影响通过合并rSTG和MTL的删除来确定目标。我们发现,合并的病变导致遗忘阈值(以75%的准确率表现)从正常的保留时间(大约30到40 s)急剧下降到大约1到2 s,从而几乎消除了听觉识别记忆,并只留下残留的回声记忆。本文是名为“ SI:听觉工作记忆”的特刊的一部分。由Elsevier B.V.发布。这是CC BY许可下的开放获取文章

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