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Insular Cortex Lesions and Morphine-Induced Suppression of Conditioned Stimulus Intake in the Rat

机译:大鼠的皮层皮损和吗啡诱导的条件性刺激摄取的抑制

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摘要

The present experiment examined the influence of insular cortex (IC) lesions on the intake of a taste stimulus in a consummatory procedure that used morphine as the unconditioned stimulus. In normal rats, morphine caused a rapid reduction in saccharin intake when the taste was novel but not when it was familiar. Irrespective of stimulus novelty, morphine had little influence on the saccharin consumption of IC-lesioned rats. The results are discussed in terms of a lesion-induced disruption of (i) a reward comparison mechanism and (ii) the perception of taste novelty.
机译:本实验通过使用吗啡作为无条件刺激的完善程序,研究了岛皮层(IC)损伤对味觉刺激摄入的影响。在正常大鼠中,当味觉新颖时,吗啡会导致糖精摄入量快速减少,但在熟悉时却不会。不论刺激新颖性如何,吗啡对IC损伤大鼠的糖精消耗几乎没有影响。根据病变引起的破坏(i)奖励比较机制和(ii)味觉新奇的观点讨论了结果。

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