首页> 外文期刊>Chemistry: A European journal >Site-specific DNA-programmed growth of fluorescent and functional silver nanoclusters
【24h】

Site-specific DNA-programmed growth of fluorescent and functional silver nanoclusters

机译:特定位置的DNA编程的荧光和功能性银纳米簇的生长

获取原文
获取原文并翻译 | 示例
           

摘要

Precise organization of metallic nanoclusters on DNA scaffolds holds great interest for nanopatterned materials that may find uses in electronics, sensors, medicine, and many other fields. Herein, we report the site-specific growth of fluorescent silver nanoclusters by using a mismatched double-stranded DNA template. Few-atom, molecular-scale Ag clusters are found to localize at the mismatched site and the metallized DNA retains its integrity. The DNA-encapsulated nanoclusters can be utilized as functional biological probes to identify single- nucleotide polymorphisms by taking advantage of the very bright fluorescence and excellent photostability of the nanoclusters. This approach offers the possibility of constructing novel DNA-based nanomaterials and nanomechanical devices with more sophisticated functions and will be highly beneficial in future biochemical, pharmaceutical, nanomechanical, and electronic applications.
机译:DNA支架上金属纳米团簇的精确组织对纳米图案化材料引起了极大的兴趣,这种材料可用于电子,传感器,医学和许多其他领域。在这里,我们通过使用不匹配的双链DNA模板报告荧光银纳米簇的特定位置生长。发现很少有原子级分子大小的Ag簇位于失配位点,金属化的DNA保持其完整性。 DNA包裹的纳米簇可以用作功能性生物探针,以利用纳米簇的非常亮的荧光和出色的光稳定性来鉴定单核苷酸多态性。这种方法提供了构建具有更复杂功能的新颖的基于DNA的纳米材料和纳米机械装置的可能性,并将在未来的生物化学,制药,纳米机械和电子应用中高度有益。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号