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Dynamic mixtures: Challenges and opportunities for the amplification and sensing of scents

机译:动态混合物:扩香和感官的挑战与机遇

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摘要

Nature generates compounds as complicated mixtures, but surprisingly little is known about the synergies or inhibitory effects of compound mixtures, which is likely to become an important research area in life sciences in the near future. Some recently developed concepts in dynamic combinatorial/covalent chemistry (DCC) have been applied to amplify (increase the intensity and long-lastingness of perception) and sense (selectively detect and discriminate) individual bioactive volatile molecules in compound mixtures. This Concept article focuses on the potential of DCC to impact and modulate the biological and chemical properties of mixtures of bioactive volatile compounds to gain a more fundamental understanding of the properties of compound mixtures in molecular recognition.
机译:大自然产生的化合物是复杂的混合物,但令人惊讶的是,人们对化合物混合物的协同作用或抑制作用知之甚少,这很可能在不久的将来成为生命科学中的重要研究领域。动态组合/共价化学(DCC)中一些最近开发的概念已应用于放大(增加感知的强度和持久性)和感知(选择性检测和区分)化合物混合物中的各个生物活性挥发性分子。本概念文章重点介绍DCC可能影响和调节生物活性挥发性化合物混合物的生物学和化学性质,以便对分子识别中化合物混合物的性质有更基本的了解。

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