Hybrid Diphenylalkyne-Dipeptide Oligomers Induce Multistrand -Sheet Formation

Ross Jonathan E.; Knipe Peter C.; Thompson Sam; Hamilton Andrew D.

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Hybrid Diphenylalkyne-Dipeptide Oligomers Induce Multistrand -Sheet Formation

机译：杂二苯炔-二肽低聚物诱导多链-片状形成

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Functionalized diphenylalkynes provide a template for the presentation of protein-like surfaces composed of multistrand -sheets. The conformational properties of three-, four-, and seven-stranded systems have been investigated in the solid- and solution-state. This class of molecule may be suitable for the mediation of therapeutically relevant protein-protein interactions.

机译：功能化的二苯基炔烃提供了用于呈现由多链片组成的蛋白样表面的模板。在固态和溶液态下，对三链，四链和七链体系的构象性质进行了研究。这类分子可能适用于介导治疗相关的蛋白质-蛋白质相互作用。

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《Chemistry: A European journal》 |2015年第39期|共4页
作者
Ross Jonathan E.; Knipe Peter C.; Thompson Sam; Hamilton Andrew D.;
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正文语种 eng
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foldamer; peptidomimetics; protein surface; protein-protein interaction; secondary structure; -sheet;

机译：折叠剂;拟肽;蛋白质表面;蛋白质-蛋白质相互作用;二级结构;-片;

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1. Hybrid Diphenylalkyne-Dipeptide Oligomers Induce Multistrand -Sheet Formation [J] . Ross Jonathan E., Knipe Peter C., Thompson Sam, Chemistry: A European journal . 2015,第39期

机译：杂二苯炔-二肽低聚物诱导多链-片状形成
2. NFGAIL Amyloid Oligomers: The Onset of Beta-Sheet Formation and the Mechanism for Fibril Formation [J] . Waldemar Hoffmann, Kristin Folmert, Johann Moschner, Journal of the American Chemical Society . 2018,第1期

机译：NFGAIL淀粉样蛋白低聚物：β-Sheet形成的开始和原纤维形成的机制。
3. High Energy Density Performance of Polymer Nanocomposites Induced by Designed Formation of BaTiO3@sheet-IikeTiO(2) Hybrid Nanofillers [J] . Su Ran, Luo Zhengdong, Zhang Dawei, The journal of physical chemistry, C. Nanomaterials and interfaces . 2016,第22期

机译：BaTiO3 @ sheet-IikeTiO（2）杂化纳米填料的设计形成诱导聚合物纳米复合材料的高能量密度性能
4. INVESTIGATIONS ON THE LASER INDUCED POLYMERIZATION OF ORGANICINORGANIC HYBRID OLIGOMERS FOR MICRO STEREO LITHOGRAPHY APPLICATIONS [C] . Andre Neumeister, Martina Carsjens, Florian Pape, International Congress on Applications of Lasers and Electro-Optics . 2010

机译：用于微立体光刻应用的有机杂交低聚物激光诱导聚合的研究
5. The halogenation, crystallization induced asymmetric transformation, and epimerization of silicon oligomers. [D] . Trankler, Kevin Anthony. 2003

机译：硅低聚物的卤化，结晶诱导不对称转化和差向异构化。
6. Anti-β-sheet conformation monoclonal antibody reduces tau and Aβ oligomer pathology in an Alzheimer’s disease model [O] . Fernando Goñi, Mitchell Martá-Ariza, Krystal Herline, 2018

机译：抗β-折叠构象单克隆抗体可降低阿尔茨海默氏病模型中的tau和Aβ低聚物病理
7. Shaking alone induces de novo conversion of recombinant prion proteins to \u3b2-sheet rich oligomers and fibrils [O] . Ladner, Carol L., Griffith, Bethany J., Wishart, David S. 2014

机译：单独摇动会导致重组病毒蛋白从头转化为富含\ u3b2sheet的寡聚物和原纤维

Hybrid Diphenylalkyne-Dipeptide Oligomers Induce Multistrand -Sheet Formation

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