First Total Synthesis of Trehalose-Containing Branched Oligosaccharide OSE-1 of Mycobacterium gordonae (Strain 990)

Chaube Manishkumar A.; Kulkarni Suvarn S.

首页> 外文期刊>Chemistry: A European journal >First Total Synthesis of Trehalose-Containing Branched Oligosaccharide OSE-1 of Mycobacterium gordonae (Strain 990)

【24h】

First Total Synthesis of Trehalose-Containing Branched Oligosaccharide OSE-1 of Mycobacterium gordonae (Strain 990)

机译：戈登分枝杆菌的海藻糖分支寡糖OSE-1的全合成（菌株990）

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The first total synthesis of the branched oligosaccharide OSE-1 of Mycobacterium gordonae (strain 990) is reported. An intramolecular aglycon delivery approach was used for constructing the desymmetrized 1,1-,-linked trehalose moiety. A [3+2] glycosylation of the trisaccharide donor and trehalose acceptor furnished the right hand side pentasaccharide. Regioselective O3 glycosylation of L-rhamnosyl 2,3-diol allowed expedient synthesis of the left hand side tetrasaccharide. The nonasaccharide was assembled in a highly convergent fashion through a [4+5] glycosylation.

机译：报道了戈登分枝杆菌（菌株990）的分支寡糖OSE-1的第一全合成。分子内糖苷配基递送方法用于构建去对称的1，1-，连接的海藻糖部分。三糖供体和海藻糖受体的[3 + 2]糖基化作用提供了右侧的五糖。 L-鼠李糖基2，3-二醇的区域选择性O3糖基化可以方便地合成左侧四糖。通过[4 + 5]糖基化以高度收敛的方式组装九糖。

著录项

来源
《Chemistry: A European journal》 |2015年第39期|共5页
作者
Chaube Manishkumar A.; Kulkarni Suvarn S.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词
1; 1 '-alpha-glycosylation; total synthesis; Mycobacterium gordonae; regioselective glycosylation; trehalose oligosaccharides;

机译：1;1'-α-糖基化;全合成;戈登分枝杆菌;区域选择性糖基化;海藻糖寡糖;

相似文献

外文文献
中文文献
专利

1. First Total Synthesis of Trehalose-Containing Branched Oligosaccharide OSE-1 of Mycobacterium gordonae (Strain 990) [J] . Chaube Manishkumar A., Kulkarni Suvarn S. Chemistry: A European journal . 2015,第39期

机译：戈登分枝杆菌的海藻糖分支寡糖OSE-1的全合成（菌株990）
2. Concise synthesis of a heptasaccharide antigen found in the cell-wall lipopolysaccharide of Mycobacterium gordonae strain 990 [J] . Rajib Panchadhayee, Anup Kumar Misra Glycoconjugate Journal . 2008,第9期

机译：戈登分枝杆菌菌株990细胞壁脂多糖中七糖抗原的合成简便
3. Concise synthesis of a heptasaccharide antigen found in the cell-wall lipopolysaccharide of Mycobacterium gordonae strain 990 [J] . Panchadhayee R, Kumar Misra A Glycoconjugate journal . 2008,第9期

机译：戈登分枝杆菌菌株990细胞壁脂多糖中七糖抗原的合成
4. SYNTHESIS OF BRANCHED OLIGOSACCHARIDES RELATED TO THE PECTIC RHAMNOGALACTURONAN I POLYSACCHARIDE [C] . Cecilia Romano, Shahid I. Awan, Mads H. Clausen International Carbohydrate Symposium . 2018

机译：与果皮菌肌肌肌酐I多糖相关的支链寡糖的合成
5. Glycals in oligosaccharide synthesis: The total synthesis of sialyl Lewis X and the total synthesis of GM4. [D] . Peterson, John Matthew. 1994

机译：寡糖合成中的乙二醇：唾液酸路易斯X的总合成和GM4的总合成。
6. Synthesis of the Oligosaccharides Related to Branching Sites of Fucosylated Chondroitin Sulfates from Sea Cucumbers [O] . Nadezhda E. Ustyuzhanina, Polina A. Fomitskaya, Alexey G. Gerbst, 2015

机译：从海参中合成与岩藻糖基化硫酸软骨素分支部位有关的寡糖
7. P981Lvot area measurement using gated ct data reclassifies aortic stenosis severity as graded by echocardiographyP982Paradoxical low-flow low-gradient aortic stenosis: an intermediate state between moderate and severe aortic stenosis?P983Can rheumatic significant mitral stenosis be a cause of paradoxical low gradient, low flow, in patients with severe aortic stenosis? an echocardiographic and outcome studyP984Clinical and hemodynamic comparison of isolated versus combined aortic and mitral stenosisP985Echocardiographic end-diastolic velocity in the proximal descending aorta should be interpreted with caution when the ascending aorta is dilated: insights from cardiovascular magnetic resonanceP987Prevalence of atrial mitral regurgitation in patients with severe mitral regurgitationP988Role of 2D/3D echocardiography in the risk stratification of endocardial lead-related tricuspid regurgitation: a single-centre study among?241 patientsP989When TEE is needed in patients with staphylococcus aureus bacteremia for the assessment of risk profile of infective endocarditis?P990Appropriateness criteria to echocardiograms for suspected infective endocarditis: experience of a tertiary referral centerP991Independent predictors of outcome in infective endocarditisP992The role of transesophageal cardiography in clinical course and prognosis of complicated infective endocarditis in critically ill patients: our 15 years experienceP993Left bundle branch block atypical pattern as a prognostic determinant in patients taken to TAVIP994Efficacy of long-term ivabradine therapy in severe systolic chronic heart failure patients with and without type 2 diabetes mellitusP995Relations between left ventricular reverse remodeling and serum markers of extracellular matrix fibrosis in dilated cardiomyopathyP996The healthy left ventricle accommodates an increasing vortex formation time for volume transfer in diastolic filling :Implications for heart failureP997Evolutionary changes of pulmonary artery pressure after left ventricular assist device implantP998Functional correlates and prognostic value of coronary flow velocity reserve by vasodilator stress echocardiography in hypertrophic cardiomyopathyP999Quantification of myocardial performance in patients with non-obstructive versus latent-obstructive hypertrophic cardiomyopathyP1000Lifelong arrhythmic risk stratification in arrhythmogenic right ventricular cardiomyopathy: distribution of events and impact of periodical reassessmentP1001Impact of fibrosis visualized by CMR in vectorcardiogram recordings of patients with suspected arrhythmogenic cardiomyopathyP1002Determinants of the beneficial effect of aldosterone antagonism on exercise capacity in heart failure with reduced ejection fractionP1003Myocardial strain values in patients with acute myocarditis and preserved ejection fraction. A magnetic resonance feature tracking studyP1004Detection of subclinical left ventricular dysfunction by speckle tracking echocardiography in patients with myocarditis without prominent wall motion abnormalitiesP1005Aborted sudden cardiac death patients aged <50 years show only mild alterations on cardiac magnetic resonance imagingP1006Relationships between subepicardial and subendocardial longitudinal strain with late gadolinium enhancement in uncomplicated hypertensive patients [O] . L. Moderato, C. Di Nora, A. Soufiani, 2016

机译：P981LVOT区域测量使用门控CT数据重新分类主动脉狭窄的严重程度，以超声心动图7982分类为分类，如二醇的低流量低梯度主动脉狭窄：中度和严重主动脉狭窄之间的中间状态？P983CAN风湿显着二尖瓣狭窄是矛盾的低梯度，低流量的原因在严重主动脉狭窄的患者中？超声心动图和结合分离的主动脉和二尖瓣术和二尖瓣狭窄的血液动力学比较的超声心动图和血液动力学比较在近期下降主动脉中应当谨慎地解释升高的主动脉：从心血管磁共振的洞察中的心血管磁共振PREValence在严重的患者中的洞察中解释二尖瓣regurgitationP988 rool 2D / 3D超声心动图在内膜内铅相关三尖瓣反流的风险分层：241例患者中的单一学习，在葡萄球菌的患者中需要TEE，用于评估感染性心内炎的风险概况？P990姑息度标准怀疑感染心内膜炎的超声心动图：第三节推荐中心的经验，感染endocardisp992在感染性Endocardisap999中的临床过程中的作用和复杂感染的预后的作用生病患者的心内膜炎：我们的15年经验训练束分支块的非典型模式作为患者的预后决定因素，以TaviP994患者在严重的收缩期慢性心力衰竭患者中患者，无型糖尿病患者左心室反向重塑和血清基质纤维化的血清标志物在扩张心肌脑肿瘤中，健康的左心室容纳舒张填充中体积转移的增加的涡旋形成时间：对左心室辅助装置Implantp998函数相关和冠状动脉速率储备的肺动脉压的肺动脉压的影响。血管扩张器应力超声心动图在肥厚性心肌病型499中，非阻塞性患者心肌表现与潜在阻塞性肥厚性心肌病的患者患者患者患者患者血小板治疗1000Lifelong心律失常风险Strati心律病学右心室心肌病的发动机：CMR患者血管瘤术治疗患者血管动脉瘤患者血管诊断患者血管心目记录中CMR的纤维化术治疗的事件和影响患有急性心肌炎和保存的喷射分数。磁共振特征跟踪STOPYP1004DETTECTECTECTET通过突出壁运动患者的斑点左心室功能障碍的亚临床左心室功能障碍，没有突出的壁运动异常，P1005aborted突发的心脏死亡患者<50岁的突然性心脏死亡患者只显示心脏磁共振术中的轻度改变，钆和肾外腺纵向应变之间的心脏磁共振成像P1006相关性简单的高血压患者增强

First Total Synthesis of Trehalose-Containing Branched Oligosaccharide OSE-1 of Mycobacterium gordonae (Strain 990)

摘要

著录项

相似文献

相关主题

期刊订阅