Identifying a Highly Active Copper Catalyst for KA(2) Reaction of Aromatic Ketones

Cai Yujuan; Tang Xinjun; Ma Shengming

首页> 外文期刊>Chemistry: A European journal >Identifying a Highly Active Copper Catalyst for KA(2) Reaction of Aromatic Ketones

【24h】

Identifying a Highly Active Copper Catalyst for KA(2) Reaction of Aromatic Ketones

机译：确定高活性铜催化剂的芳香酮的KA（2）反应

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The well-established A(3) coupling reaction of terminal alkynes, aldehydes, and amines provides the most straightforward approach to propargylic amines. However, the related reaction of ketones, especially aromatic ketones, is still a significant challenge. A highly efficient catalytic protocol has been developed for the coupling of aromatic ketones with amines and terminal alkynes, in which Cu-I, generated in situ from the reduction of CuBr2 with sodium ascorbate, has been identified as the highly efficient catalyst. Since propargylic amines are versatile synthetic intermediates and important units in pharmaceutical products, such an advance will greatly stimulate research interest involving the previously unavailable propargylic amines.

机译：末端炔烃，醛和胺的公认的A（3）偶联反应为炔丙基胺提供了最直接的方法。然而，酮，特别是芳族酮的相关反应仍然是一个重大挑战。已经开发了用于芳族酮与胺和末端炔烃的偶联的高效催化方案，其中已将通过用抗坏血酸钠还原CuBr 2原位生成的Cu-1确定为高效催化剂。由于炔丙基胺是通用的合成中间体和医药产品中的重要单元，因此这种进展将极大地激发人们对以前不可用的炔丙基胺的研究兴趣。

著录项

来源
《Chemistry: A European journal》 |2016年第7期|共4页
作者
Cai Yujuan; Tang Xinjun; Ma Shengming;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词
copper; homogeneous catalysis; propargylic amines; synthetic methods; multicomponent reactions;

机译：铜;均相催化;炔丙基胺;合成方法;多组分反应;

相似文献

外文文献
中文文献
专利

1. Identifying a Highly Active Copper Catalyst for KA(2) Reaction of Aromatic Ketones [J] . Cai Yujuan, Tang Xinjun, Ma Shengming Chemistry: A European journal . 2016,第7期

机译：确定高活性铜催化剂的芳香酮的KA（2）反应
2. One-step, efficient synthesis of combined threonine-surfactant organocatalysts for the highly enantioselective direct aldol reactions of cyclic ketones with aromatic aldehydes in the presence of water [J] . Wu C., Fu X., Ma X., Tetrahedron, Asymmetry: The International Journal for Repid Publication on all Aspects of Asymmetry in Orgainc, Inorganic, Organometallic, Physical and Bio-Organic Chemistry . 2010,第20期

机译：一步法高效合成苏氨酸表面活性剂有机催化剂，用于在水存在下环状酮与芳族醛的高度对映选择性直接羟醛反应
3. Rational combination of two privileged chiral backbones: Highly efficient organocatalysts for asymmetric direct aldol reactions between aromatic aldehydes and acylic ketones [J] . Chen JR, An XL, Zhu XY, The Journal of Organic Chemistry . 2008,第15期

机译：两个特权手性骨架的合理组合：高效有机催化剂，用于芳族醛与酰基酮之间的不对称直接羟醛反应
4. Highly Active Pd-CeO_2-NR/C (Cerium Oxide Nanorods) Bifunctional Nanocatalysts with Remarkable Stability for the Ethanol Oxidation and Oxygen Reduction Reactions in Alkaline Media [C] . P. C. Melendez-Gonzalez, M. E. Sanchez-Castro, I. L. Alonso-Lemus, Meeting of the Electrochemical Society . 2019

机译：高活性PD-CEO_2-NR / C（氧化铈纳米棒）双官能纳米催化剂具有显着稳定性的碱性介质中的乙醇氧化和氧还原反应
5. Design and synthesis of ferrocenylmethylphosphines for transition metal catalysis: From highly active cross -coupling catalysts to highly efficient addition reaction catalysts [D] . Lu, Yong 2007

机译：用于过渡金属催化的二茂铁基甲基膦的设计与合成：从高活性的交叉偶联催化剂到高效的加成反应催化剂
6. Phosphinite- and phosphite-based Type I palladacycles as highly active catalysts for addition reactions of arylboronic acids with aldehydes αβ-unsaturated ketones α-ketoesters and aldimines [O] . Ping He, Yong Lu, Qiao-Sheng Hu -1

机译：次膦酸酯和亚磷酸酯类I型Palladacycles是高活性催化剂用于芳基硼酸与醛αβ-不饱和酮α-酮酸酯和醛亚胺的加成反应
7. Phosphinite- and phosphite-based type I palladacycles as highly active catalysts for addition reactions of arylboronic acids with aldehydes, α,β-unsaturated ketones, α-ketoesters, and aldimines [O] . Ping He, Yong Lu, Qiao-Sheng Hu 2007

机译：基于磷酸盐和亚磷酸酯的I钯作为高活性催化剂，用于芳基硼酸与醛，α，β-不饱和酮，α-酮酯和醛固度的添加反应

Identifying a Highly Active Copper Catalyst for KA(2) Reaction of Aromatic Ketones

摘要

著录项

相似文献

相关主题

期刊订阅