alpha,beta-Unsaturated Gold(I) Carbenes by Tandem Cyclization and 1,5-Alkoxy Migration of 1,6-Enynes: Mechanisms and Applications

Calleja Pilar; Pablo Oscar; Ranieri Beatrice; Gaydou Morgane; Pitaval Anthony; Moreno Maria; Raducan Mihai; Echavarren Antonio M.

首页> 外文期刊>Chemistry: A European journal >alpha,beta-Unsaturated Gold(I) Carbenes by Tandem Cyclization and 1,5-Alkoxy Migration of 1,6-Enynes: Mechanisms and Applications

【24h】

alpha,beta-Unsaturated Gold(I) Carbenes by Tandem Cyclization and 1,5-Alkoxy Migration of 1,6-Enynes: Mechanisms and Applications

机译：通过串联环化和1,6-烯炔的1,5-烷氧基迁移形成α，β-不饱和金（I）卡宾烷：机理与应用

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

1,6-Enynes bearing OR groups at the propargyl position generate alpha,beta-unsaturated gold(I)-carbenes/ gold(I) stabilized allyl cations that can be trapped by alkenes to form cyclopropanes or 1,3-diketones to give products of alpha-alkylation. The best migrating group is p-nitrophenyl ether, which leads to the corresponding products without racemization. Thus, an improved formal synthesis of (+)-schisanwilsonene A has been accomplished. The different competitive reaction pathways have been delineated computationally.

机译：在炔丙基位置带有OR基团的1,6-Enynes生成α，β-不饱和的金（I）-碳烯/金（I）稳定的烯丙基阳离子，可被烯烃捕获以形成环丙烷或1,3-二酮，得到产物α-烷基化。最佳的迁移基团是对硝基苯醚，可得到相应的产物而没有外消旋作用。因此，已经完成了（+）-schisanwilsonene A的改进的形式合成。不同的竞争反应途径已经在计算上进行了描述。

著录项

来源
《Chemistry: A European journal》 |2016年第38期|共6页
作者
Calleja Pilar; Pablo Oscar; Ranieri Beatrice; Gaydou Morgane; Pitaval Anthony; Moreno Maria; Raducan Mihai; Echavarren Antonio M.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词
cycloisomerization; cyclopropanation; density functional calculations; gold; rearrangement;

机译：环异构化;环丙烷化;密度泛函计算;金;重排;

相似文献

外文文献
中文文献
专利

1. alpha,beta-Unsaturated Gold(I) Carbenes by Tandem Cyclization and 1,5-Alkoxy Migration of 1,6-Enynes: Mechanisms and Applications [J] . Calleja Pilar, Pablo Oscar, Ranieri Beatrice, Chemistry: A European journal . 2016,第38期

机译：通过串联环化和1,6-烯炔的1,5-烷氧基迁移形成α，β-不饱和金（I）卡宾烷：机理与应用
2. 1,6-Enyne Cyclizations Catalyzed by N-Heterocyclic Carbene Supported Gold Complexes: Deconvoluting Sterics and Electronics [J] . Kuppuswamy Arumugam, Bibin Varghese, Johnathan N. Brantley, European journal of organic chemistry . 2014,第3期

机译：N-杂环卡宾支持的金络合物催化的1,6-烯炔环化：去卷积立体学和电子学
3. Steric tuning of C _2-symmetric chiral N-heterocyclic carbene in gold-catalyzed asymmetric cyclization of 1,6-enynes [J] . Yamada K.-I., Matsumoto Y., Selim K.B., Tetrahedron . 2012,第22期

机译：金催化1,6-烯炔的不对称环化中C _2对称手性N-杂环卡宾的立体调节
4. Gold Catalyzed 1,5- and 1,6-Propargylic Migrations of Ethers in Cycloisomerization of 1,6- and 1,7-Enynes. [C] . Cesar R. Solorio-Alvarado, Eloisa Jimenez-Nunez, Mihai Raducan European Symposium on Organic Chemistry . 2009

机译：黄金催化1,5-和1,6-丙基偏移的醚在1,6-和1,7-兴奋剂中的环旋异构化中。
5. Enantioselective palladium(II) catalyzed 1,6-enyne cyclizations: Methodology development and application to total synthesis [D] . Corkey, Britton Kenneth 2008

机译：对映选择性钯（II）催化1，6-烯炔环化：方法学的发展和在全合成中的应用
6. αβ‐Unsaturated Gold(I) Carbenes by Tandem Cyclization and 15‐Alkoxy Migration of 16‐Enynes: Mechanisms and Applications [O] . Pilar Calleja, Dr. Óscar Pablo, Dr. Beatrice Ranieri, -1

机译：通过串联环化和16-烯炔的15-烷氧基迁移的αβ-不饱和金（I）卡宾糖：机理与应用
7. α,β-Unsaturated Gold(I) Carbenes by Tandem Cyclization and 1,5-Alkoxy Migration of 1,6-Enynes: Mechanisms and Applications [O] . Calleja, P, Pablo, O, Ranieri, B, 2016

机译：串联环化和1,6-烯炔的1,5-烷氧基迁移的α，β-不饱和金（I）卡宾烷：机理与应用
8. Mechanism of Reaction of Dimethylsilylene with Alpha, Beta-Unsaturated Epoxides [R] . Tzeng, D., Weber, W. P. 1979

机译：二甲基硅烯与α，β-不饱和环氧化物反应的机理

alpha,beta-Unsaturated Gold(I) Carbenes by Tandem Cyclization and 1,5-Alkoxy Migration of 1,6-Enynes: Mechanisms and Applications

摘要

著录项

相似文献

相关主题

期刊订阅