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首页> 外文期刊>Current Science: A Fortnightly Journal of Research >Ameliorative effects of the homeopathic medicine Lycopodium 200c and extract of Phyllanthus emblica in cadmium-induced neurotoxicity in mice
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Ameliorative effects of the homeopathic medicine Lycopodium 200c and extract of Phyllanthus emblica in cadmium-induced neurotoxicity in mice

机译：顺势疗法Lycopodium 200c和余甘子提取物对镉诱导的小鼠神经毒性的改善作用

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摘要

Cadmium is an extremely toxic heavy metal and causes neurotoxicity by inducing oxidative stress and membrane disturbances in brain. Phyllanthus emblica and Lycopodium 200c have anti-oxidative properties and are able to remove the cadmium-produced free radicals. This study investigates the role of Lycopodium 200c and Phyllanthus emblica (amlaki) in ameliorating the toxic effects of cadmium on the brain of mice. Swiss albino mice were used and divided into four different sets with one control, one induced, one with amlaki and other with both amlaki and Lycopodium treatment. To observe the changes, tests for brain acetylcholinesterase along with Mg2+ ATPase activities were performed. Results show that cadmium toxicity leads to decrease in enzymatic activities which can be reversed by the effects of amlaki and Lycopodium 200c.
机译：镉是一种剧毒的重金属，可通过诱导大脑中的氧化应激和膜紊乱而引起神经毒性。余生余甘子和石蒜200c具有抗氧化性能，能够去除镉产生的自由基。这项研究调查了石蒜200c和余甘子（amlaki）在减轻镉对小鼠大脑的毒性作用中的作用。使用瑞士的白化病小鼠，将其分为四组，一组为对照组，一组为对照组，一组为amlaki，另一组同时接受amlaki和Lycopodium处理。为了观察这些变化，进行了脑乙酰胆碱酯酶以及Mg2 + ATPase活性的测试。结果表明，镉的毒性导致酶活性的降低，这可以通过amlaki和Lycopodium 200c的作用来逆转。

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