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首页> 外文期刊>Acta Horticulturae >Antimicrobial activity of date palm ( Phoenix dactylifera ) pits extracts and its role in reducing the side effect of methyl prednisolone on some neurotransmitter content in the brain, hormone testosterone in adulthood.
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Antimicrobial activity of date palm ( Phoenix dactylifera ) pits extracts and its role in reducing the side effect of methyl prednisolone on some neurotransmitter content in the brain, hormone testosterone in adulthood.

机译：枣核（Phoenix dactylifera ）坑提取物的抗菌活性及其在减少甲基强的松龙对大脑中某些神经递质含量以及成年激素睾丸激素的副作用中的作用。

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摘要

The present work was carried out to study the impact of date palm pits' antibacterial activities on two species of pathogenic bacteria (Klebsiella pneumonia and Escherichia coli) and its role in reducing the side effect of methylprednisolone on some neurotransmitter content in the brain, hormone testosterone and testculture of male albino rats. Date palm pits are most effective in inhibiting growth of bacteria as compared with antibiotics due to differences in resistance of bacteria to anti-tested materials due to the change in membrane permeability of cells, thereby hindering the entry of enzymes or excreted by the change in the chemical composition of the constituent chemical. The results showed that the daily oral administration of pits of date palm caused the maximal increase in NE, DA and GABA content that was found in the brain stem after 2 weeks. The daily oral administration of methylprednisolone caused a decrease in NE, DA and GABA content found in the brain stem after 2 weeks. Moreover, the daily oral administration of pits of date palm and methylprednisolone caused an increase in NE content found in the brain stem after 2 weeks. The daily oral administration of pits of date palm and methylprednisolone caused a significant increase in testosterone level in serum blood of male albino rats. From the present results, it is clear that the effect of chronic oral administration of methylprednisolone and pits of data palm caused a recovery effect on testicles of male albino rats, noticing the high sperm in some tubules and tubular partial late spermatogenic arrest (spermatide level) is only seen in 10-20% of tubules. The appropriate recommendations in this study are to use nuclei dates antimicrobial on Klebsiella pneumonia and Escherichia coli than the activity of standard antibiotics and the results concluded that using intended date palm pits as a preventive measure to reduce the side effects resulting from the use of a drug methylprednisolone on the some neurotransmitter content in the brain. The hormone testosterone was determined in a testculture of male albino rats.
机译：目前的工作是研究枣椰核的抑菌活性对两种病原菌（肺炎克雷伯菌和大肠杆菌）的影响及其在减少细菌中的作用。甲泼尼龙对雄性白化病大鼠大脑中某些神经递质含量，激素睾丸激素和睾丸培养的副作用。由于细胞膜通透性的变化导致细菌对抗测试材料的抵抗力差异，因此与抗生素相比，枣椰子的凹痕最能有效地抑制细菌的生长，从而阻碍了酶的进入或因细菌的变化而被排泄。化学成分的化学组成。结果显示，每天口服大枣椰核导致2周后脑干中NE，DA和GABA含量最大增加。每天口服甲基强的松龙导致2周后脑干中NE，DA和GABA含量下降。此外，每天口服大枣棕榈和甲基强的松龙的小窝导致2周后脑干中NE含量增加。每日口服枣核和甲基强的松龙的小窝引起雄性白化病大鼠血清中睾丸激素水平的显着增加。从目前的结果来看，很明显，长期口服甲基强的松龙和掌上掌会引起雄性白化病大鼠睾丸的恢复，注意到某些小管中的高精子和肾小管的部分晚期生精停滞（杀精子水平）。仅在10-20％的小管中可见。在这项研究中，适当的建议是使用核仁日期菌对肺炎克雷伯氏菌和大肠杆菌使用抗菌药，而不是标准抗生素的活性。预防措施，以减少因使用甲基强的松龙对脑中某些神经递质含量而引起的副作用。在雄性白化病大鼠的睾丸培养物中确定了睾丸激素。

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