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首页> 外文期刊>Acta Horticulturae >Effect of sniffing of kencur (Kaemferia galangal) essential oils in rats.
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Effect of sniffing of kencur (Kaemferia galangal) essential oils in rats.

机译：嗅到kenken（Kaempferia galanga）精油对大鼠的影响。

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摘要

The purposes of this research were to separate constituent of kencur (Kaemferia galangal) essential oil and to evaluate their effects on rats by sniffing method. Separation of kencur essential oil by silica gel column chromatography resulted in 11 fractions and one pure compound. Based on GC-MS and NMR data, the pure compound was 2-propenoic acid, 3-(4-methoxyphenyl)-ethyl ester (EPMC) and fraction 2 consisted of delta -3-carene as a major component. Forty male Sprague-Dawley rats were divided into 5 groups, namely: normal group which consumed normal diet, negative control group which consumed high cholesterol diet without treatment, crude oil group, fraction 2 group and EPMC group which consumed high cholesterol diet with sniffing kencur crude oil, fraction 2 and EMPC, respectively. The results showed that the HDL, cholesterol and triglyceride levels in rat's blood which sniffed the oils for 5 weeks were significantly different for each group (P<0.05). In conclusion, fraction 2 which consisted of delta -3-carene had slimming effect while kencur crude essential oil and EPMC decreased the cholesterol and triglyceride level in rats' blood.
机译：这项研究的目的是分离Kencur（Kaemferia galangal）精油的成分，并通过嗅探方法评估其对大鼠的作用。通过硅胶柱色谱分离kencur精油可得到11个馏分和一种纯化合物。根据GC-MS和NMR数据，纯化合物为2-丙酸，3-（4-甲氧基苯基）-乙酯（EPMC），馏分2由δ-3-烯为主要成分。 40只雄性Sprague-Dawley大鼠分为5组，分别为：正常饮食组，正常饮食组，阴性对照组，未经治疗的高胆固醇饮食组，原油组，2组和EPMC组，饮用高胆固醇饮食并嗅味浓汤。原油，馏分2和EMPC。结果表明，每组嗅油5周的大鼠血液中的HDL，胆固醇和甘油三酯水平均存在显着差异（P <0.05）。总之，由δ-3-烯组成的馏分2具有减肥作用，而kencur粗精油和EPMC则可以降低大鼠血液中的胆固醇和甘油三酸酯水平。

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