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Evidence for fractal correlation properties in variations of peripheral arterial tone during REM sleep.

机译:REM睡眠过程中外周动脉张力变化中的分形相关特性的证据。

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摘要

Previous studies utilizing detrended fluctuation analysis (DFA) of heart rate variability during sleep revealed a higher fractal exponent during rapid eye movement (REM) sleep than non-REM sleep. The aim of this study was to determine whether the same difference exists in the variations of peripheral arterial tone (PAT). Finger pulse wave measured by a novel plethysmographic technique was monitored during sleep in 12 chronic heart failure patients, 8 heavy snorers, and 12 healthy volunteers. For each subject, at least two 15-min time series were constructed from the interpulse intervals and from pulse wave amplitudes during REM and non-REM sleep. Fractal scaling exponents of both types of time series were significantly higher for REM than non-REM sleep in all groups. In each of the groups and in both sleep stages, the fractal scaling exponents based on pulse wave amplitude were significantly higher than those based on pulse rate variability. A repeat of the analysis for short-, intermediate-, and long-term intervals revealed that the fractal-like exponents were evident only in the short- and intermediate-term intervals. Because PAT is a surrogate of sympathetic activation, our results indicate that variations in sympathetic activation during REM sleep have a fractal-like behavior.
机译:先前利用睡眠期间心率变异性的去趋势波动分析(DFA)进行的研究表明,快速眼动(REM)睡眠期间的分形指数高于非REM睡眠。这项研究的目的是确定周围动脉张力(PAT)的变化是否存在相同的差异。在12例慢性心力衰竭患者,8例打者和12例健康志愿者的睡眠期间,监测了通过新颖的体积描记技术测量的手指脉搏波。对于每位受试者,从REM和非REM睡眠期间的脉冲间隔和脉波幅度中至少构建了两个15分钟的时间序列。在所有组中,REM的两种时间序列的分形定标指数均显着高于非REM睡眠。在每个组中以及在两个睡眠阶段,基于脉搏波幅度的分形标度指数显着高于基于脉搏率变异性的分形标度指数。对短期,中期和长期区间进行重复分析发现,仅在短期和中期区间内,分形样指数才明显。因为PAT是交感神经激活的替代物,所以我们的结果表明,REM睡眠期间交感神经激活的变化具有分形的行为。

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