Differential bile-pancreatic secretory effects of CCK-58 and CCK-8

Joseph R. Reeve Jr.; S. Vincent Wu; David A. Keire; Kym Faull; Peter Chew; Travis E. Solomon

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Differential bile-pancreatic secretory effects of CCK-58 and CCK-8

机译：CCK-58和CCK-8对胆胰分泌的差异作用

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In this work, we 1) synthesized rat CCK-58, 2) determined the amounts and forms of rat CCK in whole blood after stimulation of its release by casein, 3) determined the potency of CCK-8 and CCK-58 peptides to displace labeled CCK-8 from CCK_A and CCK_B receptors transfected into Chinese hamster ovary (CHO) cells, and 4) examined the biological actions of CCK-8 and rat CCK-58 in an anesthetized rat model. CCK-58 was the only detected endocrine form of CCK in rat blood

机译：在这项工作中，我们1）合成了大鼠CCK-58，2）测定了酪蛋白刺激其释放后全血中大鼠CCK的量和形式，3）确定了CCK-8和CCK-58肽置换的效力从转染到中国仓鼠卵巢（CHO）细胞的CCK_A和CCK_B受体中标记的CCK-8，和4）在麻醉的大鼠模型中检查了CCK-8和大鼠CCK-58的生物学作用。 CCK-58是大鼠血液中唯一检测到的内分泌形式的CCK

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《American Journal of Physiology》 |2004年第1期|共8页
作者
Joseph R. Reeve Jr.; S. Vincent Wu; David A. Keire; Kym Faull; Peter Chew; Travis E. Solomon;
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1. Differential bile-pancreatic secretory effects of CCK-58 and CCK-8 [J] . Joseph R. Reeve Jr., S. Vincent Wu, David A. Keire, American Journal of Physiology . 2004,第3aPta1期

机译：CCK-58和CCK-8对胆胰分泌的差异作用
2. CCK-8 and CCK-58 differ in their effects on nocturnal solid meal pattern in undisturbed rats [J] . Miriam Goebel-Stengel, Andreas Stengel, Lixin Wang, American Journal of Physiology . 2012,第4aPta2期

机译：CCK-8和CCK-58对未受干扰的大鼠夜间固体膳食模式的影响不同
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4. From Endoplasmic Reticulum to Secretory Granules: Role of Zinc in the Secretory Pathway of Growth Hormone [C] . Vibor Petkovic, Maria Consolata Miletta, Primus-E. Mullis European Society of Pediatric Endocrinology Advanced Seminar in Developmental Endocrinology . 2012

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5. Differential stimulation of monocytes to secrete Secretory Leukocyte Protease Inhibitor by lipopolysaccharide of periodontal pathogens [D] . Primm, Jason Todd 2009

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6. CCK-8 and CCK-58 differ in their effects on nocturnal solid meal pattern in undisturbed rats [O] . Miriam Goebel-Stengel, Andreas Stengel, Lixin Wang, -1

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7. High-Fat Feeding During Gestation and Nursing Period have Differential Effects on the Insulin Secretory Capacity in Offspring from Normal Wistar Rats [O] . Dyrskog, Stig E.U., Gregersen, Søren, Hermansen, Kjeld 2005

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8. Regulation of Adrenal Chromaffin Cell Development by the Central Monoaminergic System: Differential Control of Norepinephrine and Epinephrine Levels and Secretory Responses (Journal Version) [R] . Lau, C. , Ross, L. L. , Whitmore, W. L. , 1987

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Differential bile-pancreatic secretory effects of CCK-58 and CCK-8

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