Physical exercise capacity is associated with coronary and peripheral vascular function in healthy young adults.

Hagg U; Wandt B; Bergstrom G; Volkmann R; Gan LM

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Physical exercise capacity is associated with coronary and peripheral vascular function in healthy young adults.

机译：在健康的年轻人中，体育锻炼的能力与冠状动脉和外周血管的功能有关。

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Short-term exercise training has been shown to improve cardiovascular function, whereas long-term effects of a physically active lifestyle, on coronary artery function in particular, are still not well studied. We explored possible relationships between physical exercise capacity and coronary and peripheral vascular function in healthy young adults. Twenty-nine healthy young male and female volunteers participated in the study. They underwent 1) basic clinical and echocardiographic characterization, 2) coronary flow velocity reserve (CFVR) measurement of the left anterior descending coronary artery (LAD), 3) common carotid artery (CCA) intima-media thickness (IMT) measurement, 4) assessment of CCA stiffness index (SI), 5) forearm flow-mediated vasodilation (FMD), and 6) submaximal exercise test. The calculated weight-adjusted maximal oxygen uptake capacity (Vo(2 max)(c)) was positively correlated to LAD CFVR and inversely correlated to IMT and SI. Also, subjects with high compared with moderate exercise capacity had higher FMD. In addition, subjects with LAD CFVR in the upper median had greater ratios between endothelium-dependent and -independent vasodilation in the forearm and lower SI in CCA. High exercise capacity due to a physically active lifestyle is associated with high coronary and peripheral artery function, indicating an early protective role of physical exercise for cardiovascular health.

机译：短期运动训练已显示可改善心血管功能，而积极运动的生活方式对尤其是冠状动脉功能的长期影响仍未得到很好的研究。我们探讨了健康年轻人中体育锻炼能力与冠状动脉和外周血管功能之间的可能关系。 29名健康的年轻男性和女性志愿者参加了这项研究。他们进行了1）基本的临床和超声心动图表征，2）左前降支冠状动脉（LAD）的冠状动脉流速储备（CFVR）测量，3）颈总动脉（CCA）内膜中膜厚度（IMT）测量，4） CCA刚度指数（SI）评估，5）前臂血流介导的血管舒张（FMD）和6）次最大运动测试。计算得出的重量调整后的最大摄氧量（Vo（2 max）（c））与LAD CFVR正相关，与IMT和SI反相关。同样，与中等运动能力相比高的受试者具有较高的口蹄疫。此外，LAD CFVR在中位数上位的受试者在前臂的内皮依赖性和非依赖性血管舒张与CCA的较低SI之间具有更高的比率。由于体育锻炼的生活方式而导致的高运动能力与高冠状动脉和外周动脉功能有关，这表明体育锻炼对心血管健康具有早期保护作用。

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《American Journal of Physiology》 |2005年第4期|共8页
作者
Hagg U; Wandt B; Bergstrom G; Volkmann R; Gan LM;
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Coronary Circulation; Exercise; Forearm; Regional Blood Flow; 冠状动脉循环; 运动(Exercise); 前臂; 局部血流;

机译：Coronary Circulation;Exercise;Forearm;Regional Blood Flow;冠状动脉循环;运动(Exercise);前臂;局部血流;

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1. Physical exercise capacity is associated with coronary and peripheral vascular function in healthy young adults. [J] . Hagg U, Wandt B, Bergstrom G, American Journal of Physiology . 2005,第4期

机译：在健康的年轻人中，体育锻炼的能力与冠状动脉和外周血管的功能有关。
2. Criterion-related validity of the short International Physical Activity Questionnaire against exercise capacity in young adults. [J] . Papathanasiou G, Georgoudis G, Georgakopoulos D, European journal of cardiovascular prevention and rehabilitation: official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology . 2010,第4期

机译：简短的国际体育锻炼问卷针对年轻人运动能力的与标准有关的有效性。
3. Effects of Tai Chi and Western exercise on physical and cognitive functioning in healthy community-dwelling older adults. [J] . Taylor Piliae RE, Newell KA, Cherin R, Journal of aging and physical activity . 2010,第3期

机译：太极拳和西方锻炼对健康的社区老年人的身体和认知功能的影响。
4. Relationship Between Physical Exercise, Nitric Oxide and Endothelial Dysfunction in Older and Young People [C] . F. Franzoni, F. Galetta, C. Morizzo, International Congress on Coronary Artery Disease . 2003

机译：老年人体育锻炼，一氧化氮和内皮功能障碍的关系
5. An exploratory study of calcium intake, physical activity, estradiol levels, and bone density in childhood cancer survivors and healthy young adults. [D] . Kass-Wolff, Jane Helen. 2005

机译：对儿童癌症幸存者和健康年轻成年人中钙摄入量，体育活动，雌二醇水平和骨密度的探索性研究。
6. Short-Term Water- and Land-Based Exercise Training Comparably Improve Exercise Capacity and Vascular Function in Patients After a Recent Coronary Event: A Pilot Randomized Controlled Trial [O] . Danijela Vasić, Marko Novaković, Mojca Božič Mijovski, -1

机译：近期进行的基于水和陆基的运动训练可在近期冠状动脉事件后相对提高患者的运动能力和血管功能：一项随机对照试验
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Physical exercise capacity is associated with coronary and peripheral vascular function in healthy young adults.

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