Wave intensity analysis of left atrial mechanics and energetics in anesthetized dogs.

Hobson TN; Flewitt JA; Belenkie I; Tyberg JV

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Wave intensity analysis of left atrial mechanics and energetics in anesthetized dogs.

机译：麻醉狗左心房力学和能量学的波强度分析。

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摘要

The left atrium (LA) acts as a booster pump during late diastole, generating the Doppler transmitral A wave and contributing incrementally to left ventricular (LV) filling. However, after volume loading and in certain disease states, LA contraction fills the LV less effectively, and retrograde flow (i.e., the Doppler Ar wave) into the pulmonary veins increases. The purpose of this study was to provide an energetic analysis of LA contraction to clarify the mechanisms responsible for changes in forward and backward flow. Wave intensity analysis was performed at the mitral valve and a pulmonary vein orifice. As operative LV stiffness increased with progressive volume loading, the reflection coefficient (i.e., energy of reflected wave/energy of incident wave) also increased. This reflected wave decelerated the forward movement of blood through the mitral valve and was transmitted through the LA, accelerating retrograde blood flow in the pulmonary veins. Although total LA work increased with volume loading,the forward hydraulic work decreased and backward hydraulic work increased. Thus wave reflection due to increased LV stiffness accounts for the decrease in the A wave and the increase in the Ar wave measured by Doppler.

机译：左心房（LA）在舒张末期起增压泵的作用，产生多普勒发射A波，并为左心室（LV）充盈做出贡献。然而，在体量负荷后和在某些疾病状态下，LA收缩不能有效填充左室，并且逆行血流（即多普勒Ar波）流入肺静脉。这项研究的目的是对洛杉矶收缩进行有力的分析，以阐明造成正向和反向流动变化的机制。在二尖瓣和肺静脉口处进行波强度分析。随着可操作的LV刚度随着逐渐增加的体积负荷而增加，反射系数（即反射波的能量/入射波的能量）也增加。该反射波使血液通过二尖瓣的向前运动减速，并通过LA传播，从而加速了肺静脉中的逆行血流。尽管总LA功随体积载荷而增加，但前进液压功减少而前进液压功增加。因此，由LV刚度增加引起的波反射说明了由多普勒测量的A波的减少和Ar波的增加。

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来源
《American Journal of Physiology》 |2007年第3期|共8页
作者
Hobson TN; Flewitt JA; Belenkie I; Tyberg JV;
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正文语种 eng
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关键词
Atrial Function; Left; 心房功能; 左;

机译：Atrial Function;Left;心房功能;左;

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1. Wave intensity analysis of left atrial mechanics and energetics in anesthetized dogs. [J] . Hobson TN, Flewitt JA, Belenkie I, American Journal of Physiology . 2007,第3期

机译：麻醉狗左心房力学和能量学的波强度分析。
2. Reduced ascending aorta distensibility relates to adverse ventricular mechanics in patients with hypoplastic left heart syndrome: Noninvasive study using wave intensity analysis [J] . BiglinoG., SchievanoS., SteedenJ.A., The Journal of Thoracic and Cardiovascular Surgery . 2012,第6期

机译：发育不良的左心综合征患者的升主动脉扩张性降低与心室力学不良有关：使用波强度分析的非侵入性研究
3. Reduced ascending aorta distensibility relates to adverse ventricular mechanics in patients with hypoplastic left heart syndrome: Noninvasive study using wave intensity analysis [J] . Giovanni Biglino, Silvia Schievano, Jennifer A. Steeden, The journal of thoracic and cardiovascular surgery . 2012,第6期

机译：发育不良的左心综合征患者的升主动脉扩张性降低与心室力学不良有关：使用波强度分析的非侵入性研究
4. Monitoring Cardiac Output and Left Atrial Pressure by Analysis of the Right Ventricular Pressure Waveform Based on Missing Output Identification [C] . Da Xu, N. Bari Olivier, Ramakrishna Mukkamala Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2009

机译：基于缺失输出识别，通过分析右心室压力波形监测心输出和左心室压力
5. Assessment of left atrial mechanics and energetics in dogs using wave intensity analysis [D] . Hobson, Tracy Nicole. 2006

机译：利用波强度分析评估狗的左心房力学和能量
6. A review of wave mechanics in the pulmonary artery with an emphasis on wave intensity analysis [O] . Junjing Su, Ole Hilberg, Luke Howard, -1

机译：回顾肺动脉的波力学着重于波强度分析
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Wave intensity analysis of left atrial mechanics and energetics in anesthetized dogs.

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