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首页> 外文期刊>American Journal of Physiology >Muscle metabolic responses to exercise above and below the 'critical power' assessed using 31P-MRS.
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Muscle metabolic responses to exercise above and below the 'critical power' assessed using 31P-MRS.

机译：使用31P-MRS评估肌肉对高于或低于“临界力量”运动的代谢反应。

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摘要

We tested the hypothesis that the asymptote of the hyperbolic relationship between work rate and time to exhaustion during muscular exercise, the "critical power" (CP), represents the highest constant work rate that can be sustained without a progressive loss of homeostasis [as assessed using (31)P magnetic resonance spectroscopy (MRS) measurements of muscle metabolites]. Six healthy male subjects initially completed single-leg knee-extension exercise at three to four different constant work rates to the limit of tolerance (range 3-18 min) for estimation of the CP (mean +/- SD, 20 +/- 2 W). Subsequently, the subjects exercised at work rates 10% below CP (CP) for as long as possible, while the metabolic responses in the contracting quadriceps muscle, i.e., phosphorylcreatine concentration ([PCr]), P(i) concentration ([P(i)]), and pH, were estimated using (31)P-MRS. All subjects completed 20 min of CP exercise was 14.7 +/- 7.1 min. During CP exercise, however, [PCr] continued to fall to the point of exhaustion and [P(i)] and pH changed precipitously to values that are typically observed at the termination of high-intensity exhaustive exercise (end-exercise values = 26 +/- 16% of baseline [PCr], 564 +/- 167% of baseline [P(i)], and pH 6.87 +/- 0.10, all P < 0.05 vs.
机译：我们检验了以下假设：肌肉运动过程中工作率与疲惫时间之间的双曲线关系的渐近线“临界功率”（CP）表示可​​以维持的最高恒定工作率，而不会逐渐失去稳态。 （31）P磁共振波谱（MRS）测量肌肉代谢产物]。六名健康的男性受试者最初以三到四个不同的恒定工作速率完成单腿膝盖伸展运动，直至达到估计CP的耐受极限（范围3-18分钟）（平均+/- SD，20 +/- 2 W）。随后，受试者尽可能长时间以低于CP（ CP）10％的运动速率运动，而收缩的股四头肌中的代谢反应即磷酸肌酸浓度（[使用（31）P-MRS估算PCr]），P（i）浓度（[P（i）]）和pH。所有受试者均完成20分钟的 CP运动期间的耐受极限为14.7 +/- 7.1分钟。在 CP锻炼期间，[PCr]继续下降至精疲力尽，[P（i）]和pH急剧变化为高强度力竭锻炼结束时通常观察到的值（最终运动值=基线[PCr]的26 +/- 16％，基线[P（i）]的564 +/- 167％和pH值6.87 +/- 0.10，所有P <0.05 vs.

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