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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Impact of Lower Mediastinal Lymphadenectomy for the Treatment of Esophagogastric Junction Carcinoma
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Impact of Lower Mediastinal Lymphadenectomy for the Treatment of Esophagogastric Junction Carcinoma

机译：下纵隔淋巴结清扫术治疗食管胃交界癌的效果

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Aim: To define the optimal extent of resection for esophagogastric junction (EGJ) carcinoma. Patients and Methods: We retrospectively reviewed medical records of 193 patients with EGJ adenocarcinoma or squamous cell carcinoma who underwent surgery at the Kitasato University. An index was calculated to evaluate the therapeutic value of lymphadenectomy. Results: The following factors were identified as independent predictors of poor survival: (y)pT3-4, (y)pN3, ly2-3, no performance of splenectomy and R1-2. Although metastases were found in mediastinal lymph-nodes in patients with esophageal invasion of <= 30 mm, the index was 0 for all mediastinal lymph-nodes. By contrast, in patients with esophageal invasion of >30 mm, the index was 13.9 for the No. 110 nodes, which was the second highest after the index for the No. 1 nodes. Conclusion: In EGJ cancer patients with esophageal invasion of >30 mm, aggressive lower mediastinal lymphadenectomy with RO resection is required to obtain the best result.
机译：目的：确定食管胃交界处（EGJ）癌的最佳切除范围。患者和方法：我们回顾性地回顾了北里大学（Kitasato University）接受手术的193例EGJ腺癌或鳞状细胞癌患者的病历。计算指标以评估淋巴结清扫术的治疗价值。结果：以下因素被确定为生存不良的独立预测因素：（y）pT3-4，（y）pN3，ly2-3，未行脾切除术和R1-2。尽管食管浸润<= 30 mm的患者在纵隔淋巴结中发现转移，但所有纵隔淋巴结的指数均为0。相比之下，在食管浸润> 30 mm的患者中，第110淋巴结的指数为13.9，仅次于第1淋巴结的指数第二高。结论：对于食管浸润> 30 mm的EGJ癌症患者，需要行积极的下纵隔淋巴结清扫术及RO切除术才能获得最佳效果。

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