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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Single Hepatocellular Carcinoma Smaller than 2 cm: Are Ethanol Injection and Radiofrequency Ablation Equally Effective?
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Single Hepatocellular Carcinoma Smaller than 2 cm: Are Ethanol Injection and Radiofrequency Ablation Equally Effective?

机译：小于2 cm的单个肝细胞癌：乙醇注射和射频消融是否同样有效？

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Background/Aim: The impact of radiofrequency ablation (RFA) and percutaneous ethanol injection (PEI) on survival in patients with small hepatocellular carcinoma (HCC) is unclear. We compared their efficacy in cirrhotics with single HCC cm. Patients and Methods: Two hundred forty-four cirrhotics with single HCC cm treated with PEI (108 cases) or RFA (136 cases) were enrolled in the study. Eighty-one patients in each group were selected for propensity score matching analysis. Results: The five-year survival was not significantly different (64.7% in PEI and 72.9% in RFA group) but the 5-year recurrence (73.3% in PEI and 49% in RFA group, p=0.023) and local tumor progression (49% in PEI and 30.1% in RFA group, p=0.018) were higher in the PEI group. Conclusion: PEI and RFA are equally effective in treating HCCs smaller than 2 cm in terms of 5-year survival, despite higher cumulative and local recurrence rates, in patients treated with PEI.
机译：背景/目的：射频消融（RFA）和经皮乙醇注射（PEI）对小肝细胞癌（HCC）患者生存的影响尚不清楚。我们比较了它们在单发HCC cm肝硬化患者中的疗效。患者和方法：研究纳入了接受PEI（108例）或RFA（136例）治疗的单发HCC cm肝硬化患者44例。选择每组中的81名患者进行倾向评分匹配分析。结果：五年生存率无显着差异（PEI为64.7％，RFA组为72.9％），但5年复发率（PEI为73.3％，RFA组为49％，p = 0.023）和局部肿瘤进展（ PEI组的PEI较高，PEI组为49％，RFA组为30.1％，p = 0.018）。结论：尽管PEI治疗的患者累积和局部复发率更高，但是从5年生存率方面来说，PEI和RFA在治疗小于2 cm的肝癌方面同样有效。

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