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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Predicting Survival of Patients with Metastatic Epidural Spinal Cord Compression from Cancer of the Head-and-Neck
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Predicting Survival of Patients with Metastatic Epidural Spinal Cord Compression from Cancer of the Head-and-Neck

机译：从头颈部癌症预测转移性硬膜外脊髓压迫患者的生存

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Aim: To develop an instrument for estimating survival after irradiation for metastatic epidural spinal cord compression (MESCC) from head and neck cancer. Patients and Methods: In 58 patients, eleven factors were evaluated for influence on survival: age, gender, performance status, tumor site, time from cancer diagnosis until MESCC, affected vertebrae, walking ability, further osseous lesions, organ metastases, time developing motor deficits and radiation regimen. Factors with significant association with survival or a trend (multivariate analysis) were used for scoring. Results: Walking ability, visceral metastases and time to developing motor deficits were included in the score. Scoring points were calculated by dividing 6-month survival rates by 10. Patients' scores were obtained from adding the points of the three factors. Four groups were created, 7-10, 12-15, 16-18 and 21 points. Six-month survival rates were 0%, 27%, 71% and 100% (p<0.001). Conclusion: With this new instrument, one can estimate 6-month survival probabilities of patients with MESCC from head-and-neck cancer.
机译：目的：开发一种评估头颈癌转移性硬膜外脊髓压迫（MESCC）照射后存活的仪器。患者和方法：在58例患者中，评估了11个因素对生存的影响：年龄，性别，行为状态，肿瘤部位，从癌症诊断到MESCC的时间，椎骨受影响，行走能力，进一步的骨性病变，器官转移，运动时间的发展缺陷和放射疗法。与生存或趋势显着相关的因素（多元分析）用于评分。结果：得分包括步行能力，内脏转移和发展为运动功能障碍的时间。通过将6个月生存率除以10来计算得分。患者得分是通过将三个因素的得分相加而得出的。创建了四个组，分别是7-10、12-15、16-18和21分。六个月生存率分别为0％，27％，71％和100％（p <0.001）。结论：使用这种新仪器，可以估计头颈癌患者的MESCC的6个月生存率。

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