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首页> 外文期刊>Antimicrobial agents and chemotherapy. >First report of metallo-β-lactamase NDM-5-producing Escherichia coli in Japan
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First report of metallo-β-lactamase NDM-5-producing Escherichia coli in Japan

机译:日本生产金属-β-内酰胺酶NDM-5的大肠杆菌的首次报道

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摘要

Reports of carbapenemase-producing carbapenem-resistant Enterobacteriaceae are increasing worldwide (1). Among the newly emerged carbapenemases, New Delhi metallo-P-lactamase 1 (NDM-1) represents the latest threat to public health. Since it was first described in 2009 (2), NDM-producing organisms have become endemic on the Indian subcontinent and likely also in several Middle Eastern and Balkan countries, and numerous transfers have been recorded worldwide (3). To our knowledge, NDM is uncommon in Japan, with only six sporadic cases of NDM-1 producers reported since the first case in 2009 (1). This is the first report of the detection of an NDM-5-producing Esche-richia colt clinical isolate in Japan.
机译:在世界范围内,产生碳青霉烯酶的耐碳青霉烯酶的肠杆菌科的报告正在增加(1)。在新出现的碳青霉烯酶中,新德里金属-β-内酰胺酶1(NDM-1)代表了对公共健康的最新威胁。自2009年首次描述以来(2),生产NDM的生物已成为印度次大陆的特有种,而且很可能也出现在中东和巴尔干的一些国家,并且在世界范围内已记录了许多转移(3)。据我们所知,NDM在日本并不常见,自2009年第一例以来,​​仅报告了零星的NDM-1生产者案例(1)。这是在日本检测到生产NDM-5的埃希里希菌柯尔特临床分离株的第一份报告。

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