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首页> 外文期刊>Applied optics >Blood oxygenation measurements by multichannel reflectometry on the venous and arterial structures of the retina
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Blood oxygenation measurements by multichannel reflectometry on the venous and arterial structures of the retina

机译：通过多通道反射法对视网膜的静脉和动脉结构进行血液氧合测量

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The aim of the present study was to propose a model and a method to derive the oxyhemoglobin blood content in the retinal veins and arteries by full spectrum reflectometry measurements in the spectral zone from 430 to 680 nm. We proposed a mathematical equation expressed as a linear combination of two terms S_(OHb)(lambda) and S_(Hb)(lambda) representing the normalized spectral absorption functions of the hemoglobin and the oxyhemoglobin, one term (lambda)~(-n) representing the ocular media absorption with scattering, and a family of multi-Gaussian functions, which usefully compensate for the noncompatibility of the model and the experimental data in the red spectral zone. The present paper suggests that the spectral reflection function in the area from 520 to 580 nm is optimal in calculating the oxyhemoglobin concentration of the blood contained in the endothelial structures of retinal vessels. The model calculation needs a function (1/lambda)~(-n) that corrects for the ocular media absorption and light scattering on the vessels' structures. For the spectral area of lights with wavelength larger than 580 nm, the reflected light represents mainly the light scattering on the red blood cells.
机译：本研究的目的是提出一种模型和方法，通过在430至680 nm的光谱区域中进行全光谱反射测量，得出视网膜静脉和动脉中氧合血红蛋白的血液含量。我们提出了一个数学方程，表示为代表血红蛋白和氧合血红蛋白的归一化光谱吸收函数的两项S_（OHb）（lambda）和S_（Hb）（lambda）的线性组合，一项为（lambda）〜（-n ）代表具有散射的眼介质吸收，以及一系列高斯函数，这些函数可有效补偿模型和红色光谱区中的实验数据的不兼容性。本文认为，在计算视网膜血管内皮结构中所含血液的氧合血红蛋白浓度时，在520至580 nm范围内的光谱反射函数是最佳的。模型计算需要函数（1 /λ）〜（-n）来校正眼介质在血管结构上的吸收和光散射。对于波长大于580 nm的光的光谱区域，反射光主要代表在红血球上散射的光。

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