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首页> 外文期刊>Bioinformatics >ARGs-OAP: online analysis pipeline for antibiotic resistance genes detection from metagenomic data using an integrated structured ARG-database
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ARGs-OAP: online analysis pipeline for antibiotic resistance genes detection from metagenomic data using an integrated structured ARG-database

机译:ARGs-OAP:使用集成的结构化ARG数据库从宏基因组学数据中检测抗生素抗性基因的在线分析管道

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摘要

Motivation: Environmental dissemination of antibiotic resistance genes (ARGs) has become an increasing concern for public health. Metagenomics approaches can effectively detect broad profiles of ARGs in environmental samples; however, the detection and subsequent classification of ARG-like sequences are time consuming and have been severe obstacles in employingmetagenomic methods. We sought to accelerate quantification of ARGs inmetagenomic data from environmental samples.
机译:动机:抗生素抗性基因(ARG)在环境中的传播已成为公众健康日益关注的问题。元基因组学方法可以有效检测环境样品中ARG的广泛概况;然而,类ARG序列的检测和随后的分类是费时的,并且在采用元基因组学方法方面是严重的障碍。我们试图加速对来自环境样品的ARGs元数据进行定量分析。

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