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Transfusion trigger: when to transfuse?

机译:输血触发:何时输血?

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The decision to transfuse a hospitalized patient must balance the known risks of transfusion with the need to provide adequate tissue oxygenation and the appropriate utilization of blood as a scarce resource. The minimum tolerated hemoglobin level is not well established, and considerable variation exists in intensivists' transfusion practices. Conventional transfusion triggers of 100 g/l have been challenged by reports indicating that aerobic metabolism is supported by hemoglobin levels of 50 g/l or less. Evidence from randomized trials also indicates that withholding transfusions may result in improved outcomes. Arbitrary numeric hemoglobin triggers, however, cannot supercede intervention based on individual physiologic need and clinical circumstances.
机译:为住院患者输血的决定必须在已知的输血风险与提供足够的组织氧合和适当利用血液作为稀缺资源的需求之间取得平衡。最低的耐受血红蛋白水平尚不明确,在强化医生的输血实践中存在相当大的差异。报导表明有氧代谢由50 g / l或更低的血红蛋白水平支持,从而挑战了传统的100 g / l的输血触发条件。随机试验的证据还表明,不输血可能会改善转归。但是,任意数量的血红蛋白触发器均不能取代基于个体生理需要和临床情况的干预措施。

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