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Synthesis and electrochemical study of a hybrid structure based on PDMS-TEOS and titania nanotubes for biomedical applications

机译:基于PDMS-TEOS和二氧化钛纳米管的生物医学混合结构的合成和电化学研究

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摘要

Metallic implants and devices are widely used in the orthopedic and orthodontic clinical areas. However, several problems regarding their adhesion with the living tissues and inflammatory responses due to the release of metallic ions to the medium have been reported. The modification of the metallic surfaces and the use of biocompatible protective coatings are two approaches to solve such issues. In this study, in order to improve the adhesion properties and to increase the corrosion resistance of metallic Ti substrates we have obtained a hybrid structure based on TiO_2 nanotubular arrays and PDMS-TEOS films. TiO_2 nanotubes have been prepared with two different diameters by means of electrochemical anodization. PDMS-TEOS films have been prepared by the sol-gel method. The morphological and the elemental analysis of the structures have been investigated by scanning electron microscopy and energy dispersive spectroscopy (EDS). Electrochemical impedance spectroscopy (EIS) and polarization curves have been performed during immersion of the samples in Kokubo's simulated body fluid (SBF) at 37 °C to study the effect of structure layers and tube diameter on the protective properties. The obtained results show that the modification of the surface structure of TiO_2 and the application of PDMSTEOS film is a promising strategy for the development of implant materials.
机译:金属植入物和设备广泛用于矫形和正畸临床领域。然而,由于金属离子向培养基的释放,已经报道了一些关于它们与活组织的粘附和炎症反应的问题。金属表面的改性和生物相容性保护涂层的使用是解决此类问题的两种方法。在这项研究中,为了改善金属Ti基材的粘附性能并提高其耐腐蚀性,我们获得了一种基于TiO_2纳米管阵列和PDMS-TEOS膜的混合结构。 TiO_2纳米管已经通过电化学阳极氧化制备了两种不同的直径。 PDMS-TEOS膜已通过溶胶-凝胶法制备。结构的形态和元素分析已通过扫描电子显微镜和能量色散光谱法(EDS)进行了研究。在将样品浸入小久保的模拟体液(SBF)中于37°C的过程中,已进行了电化学阻抗谱(EIS)和极化曲线,以研究结构层和管径对防护性能的影响。所得结果表明,TiO_2表面结构的改性和PDMSTEOS膜的应用是开发植入材料的有前途的策略。

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