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首页> 外文期刊>Neuroscience Letters: An International Multidisciplinary Journal Devoted to the Rapid Publication of Basic Research in the Brain Sciences >Measuring sub-millisecond delays in spiking activity with millisecond time-bins.
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Measuring sub-millisecond delays in spiking activity with millisecond time-bins.

机译：使用毫秒时间间隔来测量峰值活动中的亚毫秒延迟。

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摘要

Recent evidence indicates that sub-millisecond delays in neuronal spiking activity may be relevant for neural coding. Estimates of these delays are usually made from cross-correlation histograms (CCH) binned to 1ms. We investigated the degree to which it is possible to measure delays with sub-millisecond precision when one computes CCHs with bin sizes > or =1ms. To this end, we introduced sub-millisecond shifts into spike trains recorded from cat visual cortex. The bin sizes of 1/2 to 2ms were the most optimal for measuring the artificial shifts, even when detecting shifts smaller than 0.5ms. The results suggest that preferably, one should use CCHs with approximately 1ms binning even when investigating differences in delays considerably smaller than 1ms.
机译：最近的证据表明，神经元尖峰活动的亚毫秒级延迟可能与神经编码有关。这些延迟的估计通常由装在1ms的互相关直方图（CCH）进行。我们研究了当人们计算bin大小>或= 1ms的CCH时，可以以亚毫秒精度测量延迟的程度。为此，我们将亚毫秒级转换引入了从猫视觉皮层记录的峰值序列中。 1/2到2ms的分档大小对于测量人为偏移最为理想，即使检测到小于0.5ms的偏移也是如此。结果表明，即使调查延迟小于1ms的差异，最好也应使用合并时间约为1ms的CCH。

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