首页> 外文期刊>Neuroscience: An International Journal under the Editorial Direction of IBRO >FINGER-SPECIFIC LOSS OF INDEPENDENT CONTROL OF MOVEMENTS IN MUSICIANS WITH FOCAL DYSTONIA
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FINGER-SPECIFIC LOSS OF INDEPENDENT CONTROL OF MOVEMENTS IN MUSICIANS WITH FOCAL DYSTONIA

机译:手指运动障碍独立控制的手指特定损失

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The loss of independent control of finger movements impairs the dexterous use of the hand. Focal hand dystonia is characterised by abnormal structural and functional changes at the cortical and subcortical regions responsible for individuated finger movements and by the loss of surround inhibition in the finger muscles. However, little is known about the pathophysiological impact of focal dystonia on the independent control of finger movements. Here we addressed this issue by asking pianists with and without focal dystonia to repetitively strike a piano key with one of the four fingers as fast as possible while the remaining digits kept the adjacent keys depressed. Using principal component analysis and cluster analysis to the derived keystroke data, we successfully classified pianists according to the presence or absence of dystonic symptoms with classification rates and cross-validation scores of approximately 90%. This confirmed the effects of focal dystonia on the individuated finger movements. Interestingly, the movement features that contributed to successful classification differed across fingers. Compared to healthy pianists, pianists with an affected index finger were characterised predominantly by stronger keystrokes, whereas pianists with affected middle or ring fingers exhibited abnormal temporal control of the keystrokes, such as slowness and rhythmic inconsistency. The selective alternation of the movement features indicates a finger-specific loss of the independent control of finger movements in focal dystonia of musicians.
机译:失去对手指运动的独立控制会损害手的灵巧使用。局灶性手张力障碍的特征是负责个体手指运动的皮质和皮质下区域的异常结构和功能改变,以及手指肌肉周围抑制的丧失。然而,关于局灶性肌张力障碍对手指运动的独立控制的病理生理影响知之甚少。在这里,我们通过要求有或没有局灶性肌张力障碍的钢琴演奏者尽快用四个手指之一反复敲击钢琴琴键来解决这个问题,而其余的数字则使相邻琴键保持按下状态。使用主成分分析和聚类分析得出的击键数据,我们根据是否存在肌张力异常症状成功地对钢琴家进行了分类,分类率和交叉验证得分约为90%。这证实了局灶性肌张力障碍对个体手指运动的影响。有趣的是,促成成功分类的运动特征因手指而异。与健康的钢琴演奏者相比,食指受影响的钢琴演奏者的主要特点是击键强度更高,而中指或无名指受影响的钢琴演奏者对按键的时间控制表现出异常,例如缓慢和节奏上的不一致。运动特征的选择性交替指示在音乐家的局部肌张力障碍中对手指运动的独立控制失去了特定于手指的感觉。

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