• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>RSC Advances >Wettability gradient-induced alignment of peptide nanotubes as templates for biosensing applications
【24h】

Wettability gradient-induced alignment of peptide nanotubes as templates for biosensing applications

机译：润湿性梯度诱导的肽纳米管比对作为生物传感应用的模板

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Self-assembled diphenylalanine (FF) peptide nanotubes (PNTs) have attracted significant attention due to their well-ordered supramolecular structure and wide range of functional capabilities that may enable potential nanobiotechnology applications. However, self-assembled PNTs are generally inhomogeneous at the macroscale, which has limited their potential use. Reproducibly controlling the assembly and alignment of PNTs is therefore critical to enable the widespread use of PNTs, e.g., in sensing applications. In this study, a surface patterning technique based on UV/ozone exposure through a mask is used to align PNTs. Exposed regions become hydrophilic, leading to directed spreading of the FF solution and alignment of the PNTs that improves as the difference in wettability between adjacent regions increases. Alignment was further found to depend on the concentration-and temperature-dependent diameter of the PNTs formed and the size of the hydrophilic area. Finally, aligned PNTs decorated with silver nanoparticles are used to sense an analyte molecule using surface enhanced Raman spectroscopy.
机译：自组装的二苯丙氨酸（FF）肽纳米管（PNT）由于其有序的超分子结构和广泛的功能性而备受关注，这些功能性可能使潜在的纳米生物技术应用成为可能。然而，自组装的PNT通常在宏观上是不均匀的，这限制了它们的潜在用途。因此，可再现地控制PNT的组装和对准对于例如在感测应用中能够广泛使用PNT是至关重要的。在这项研究中，基于通过掩模暴露于紫外线/臭氧的表面图案化技术用于对准PNT。暴露的区域变成亲水性的，导致FF溶液的定向扩散和PNT的排列随着相邻区域之间润湿性差异的增加而改善。进一步发现排列依赖于所形成的PNT的浓度和温度相关的直径和亲水区域的大小。最后，用表面修饰的拉曼光谱法将用银纳米颗粒修饰的对齐的PNT用于感测分析物分子。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号